Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1128 Articles

Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors

THIBORD, F., Klarin, D., Brody, J. A., Chen, M.-H., Levin, M. G., Chasman, D. I., Goode, E. L., Hveem, K., Teder-Laving, M., Martinez-Perez, A., Aissi, D., Daian-Bacq, D., Ito, K., Natarajan, P., Lutsey, P. L., Nadkarni, G. N., Cuellar-Partida, G., Wolford, B. N., Pattee, J. W., Kooperberg, C., Braekkan, S. K., Li-Gao, R., Saut, N., Sept, C., Germain, M., Judy, R. L., Wiggins, K. L., Ko, D., O'Donnell, C., Taylor, K. D., Giulianini, F., De Andrade, M., Nost, T. H., Boland, A., Empana, J.-P., Koyama, S., Gilliland, T., Do, R., Wang, X., Zhou, W., Soria, J. M., Souto, J. C., Pankratz, N., Haessl

10.1101/2022.03.04.22271003 — Posted: 2022-03-08

Defining cellular population dynamics at single cell resolution during prostate cancer progression

Germanos, A. A., Arora, S., Zheng, Y., Goddard, E. T., Coleman, I. M., Ku, A. T., Wilkinson, S., Amezquita, R. A., Zager, M., Long, A., Yang, Y. C., Bielas, J. H., Gottardo, R., Ghajar, C. M., Nelson, P. S., Sowalsky, A. G., Setty, M., Hsieh, A. C.

10.1101/2022.03.02.482711 — Posted: 2022-03-04

Multi-ancestry meta-analysis identifies 2 novel loci associated with ischemic stroke and reveals heterogeneity of effects between sexes and ancestries

Surakka, I., Wu, K.-H. H., Hornsby, W. E., Wolford, B., Shen, F., Zhou, W., Huffman, J. E., Pandit, A., Hu, Y., Brumpton, B., Skogholt, A. H., Gabrielsen, M. E., Walters, R., The TOPMed Stroke Working Group, , Million Veteran Program (MVP), , Hveem, K., Kooperberg, C., Zollner, S., Wilson, P. W. F., Sutton, N. R., Daly, M., Neale, B., Willer, C. J., Global Biobank Meta-analysis Initiative (GBMI)

10.1101/2022.02.28.22271647 — Posted: 2022-03-01

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

Starr, T. N., Greaney, A. J., Hannon, W. W., Loes, A. N., Hauser, K., Dillen, J. R., Ferri, E., Ghez Farrell, A., Dadonaite, B., McCallum, M., Matreyek, K. A., Corti, D., Veesler, D., Snell, G., Bloom, J. D.

10.1101/2022.02.24.481899 — Posted: 2022-02-26

Spillover Benefit of Pre-Exposure Prophylaxis for HIV Prevention: Evaluating the Importance of Effect Modification using an Agent-Based Model

Buchanan, A., Park, C., Bessey, S., Goedel, W., Murray, E. J., Friedman, S., Halloran, M. E., Katenka, N., Marshall, B.

10.1101/2022.02.22.22271345 — Posted: 2022-02-23

Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge

Malhi, H., Homad, L. J., Wan, Y.-H., Poudel, B., Fiala, B., Borst, A. J., Wang, J. Y., Walkey, C., Price, J., Wall, A., Singh, S., Moodie, Z., Handa, S., Correnti, C., Stoddard, B. L., Veesler, D., Pancera, M., Olson, J., King, N. P., McGuire, A.

10.1101/2022.02.17.480914 — Posted: 2022-02-19

NUCLEAR RETENTION OF LEPTIN/UPD2 REGULATES ORGANISMAL RESILIENCE TO NUTRIENT EXTREMES

Poling, M. E., Sullivan, C. E., Madan, A., Kelly, K. P., Brent, A. E., Dubrulle, J., Raghavan, P., Rajan, A.

10.1101/2021.01.29.428913 — Posted: 2022-02-18

Associations between SARS-CoV-2 variants and risk of COVID-19 hospitalization among confirmed cases in Washington State: a retrospective cohort study

Paredes, M. I., Lunn, S., Famulare, M., Frisbie, L. A., Painter, I., Burstein, R., Roychoudhury, P., Xie, H., Bakhash, S. A. M., Perez, R., Lukes, M., Ellis, S., Sathees, S., Mathias, P. C., Greninger, A., Starita, L. M., Frazar, C. D., Ryke, E., Zhong, W., Gamboa, L., Threlkeld, M., Lee, J., McDermot, E., Truong, M., Nickerson, D. A., Bates, D. L., Hartman, M. E., Haugen, E., Nguyen, T. N., Richards, J. D., Rodriguez, J. L., Stamatoyannopoulos, J., Thorland, E., Melly, G., Dykema, P. E., MacKellar, D. C., Gray, H. K., Singh, A., Peterson, J. M., Russell, D., Torres, L. M., Lindquist, S., Bedf

10.1101/2021.09.29.21264272 — Posted: 2022-02-16

Olverembatinib inhibits SARS-CoV-2-Omicron variant-mediated cytokine release

Chan, M., Holland, E., Gujral, T.

10.1101/2022.02.07.479443 — Posted: 2022-02-09

Narrow transmission bottlenecks and limited within-host viral diversity during a SARS-CoV-2 outbreak on a fishing boat

Hannon, W. H., Roychoudhury, P., Xie, H., Shrestha, L., Addetia, A., Jerome, K. R., Greninger, A. L., Bloom, J. D.

10.1101/2022.02.09.479546 — Posted: 2022-02-09

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