Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1054 Articles

Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses.

Arnold, E. A., Kaai, R. J., Leung, K., Brinkley, M. R., Kelnhofer-Millevolte, L. E., Guo, M. S., Avgousti, D. C.

10.1101/2023.04.17.537247 — Posted: 2023-04-18

Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics

Chan, T. F., Rui, X., Conti, D. V., Fornage, M., Graff, M., Haessler, J., Haiman, C., Highland, H. M., Jung, S. Y., Kenny, E., Kooperberg, C., Le Marchland, L., North, K. E., Tao, R., Wojcik, G., Gignoux, C. R., PAGE Consortium, , Chiang, C. W., Mancuso, N.

10.1101/2023.04.10.536252 — Posted: 2023-04-18

Hypercholesterolemia aggravates in-stent restenosis in rabbits: a mitigating effect of stent surface modification with CD47-derived peptide

Fishbein, I., Inamdar, V. V., Alferiev, I. S., Bratinov, G., Zviman, M. M., Yekhilevsky, A., Nagaswami, C., Gardiner, K. L., Levy, R. J., Stachelek, S. J.

10.1101/2023.02.27.530304 — Posted: 2023-04-15

Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations

Li, S., Wong, A., Sun, H., Bhatia, V., Javier, G., Jana, S., Mongomery, R. B., Wright, J. L., Lam, H.-M., Hsieh, A. C., Faltas, B. M., Haffner, M. C., Lee, J. K.

10.1101/2023.04.12.536652 — Posted: 2023-04-14

Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment

Wrenn, E. D., Apfelbaum, A. A., Rudzinski, E. R., Deng, X., Jiang, W., Sud, S., Van Noord, R. A., Newman, E. A., Garcia, N. M., Hoglund, V. J., Bhise, S. S., Kanaan, S. B., Waltner, O. G., Furlan, S. N., Lawlor, E. R.

10.1101/2023.04.12.536619 — Posted: 2023-04-13

Microbiome Preterm Birth DREAM Challenge: Crowdsourcing Machine Learning Approaches to Advance Preterm Birth Research

Golob, J. L., Oskotsky, T. T., Tang, A., Roldan, A., Chung, V., Ha, C. W. Y., Wong, R., Flynn, K., Parraga-Leo, A., Wibrand, C., Minot, S. S., Andreoletti, G., Kosti, I., Bletz, J., Nelson, A., Gao, J., Wei, Z., Chen, G., Tang, Z.-Z., Novielli, P., Romano, D., Pantaleo, E., Amoroso, N., Monaco, A., Vacca, M., De Angelis, M., Bellotti, R., Tangaro, S., Kuntzleman, A., Bigcraft, I., Techtmann, S., Bae, D., Kim, E., Jeon, J., Joe, S., The Preterm Birth DREAM Community, , Theis, K., Ng, S. Q. Y., Lee, Y., Diaz-Gimeno, P., MacIntyre, D., Stolovitzky, G., Lynch, S. V., Albrecht, J., Romero, R., Ste

10.1101/2023.03.07.23286920 — Posted: 2023-04-11

Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses

Lubow, J., Levoir, L. M., Ralph, D. K., Belmont, L., Contreras, M., Cartwright-Acar, C. H., Kikawa, C., Kannan, S., Davidson, E., Doranz, B. J., Duran, V., Sanchez, D. E., Sanz, A. M., Rosso, F., Einav, S., Matsen, F. A., Goo, L.

10.1101/2023.04.09.536175 — Posted: 2023-04-11

Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking

Liu, L., Casner, R. G., Guo, Y., Wang, Q., Iketani, S., Chan, J. F.-W., Yu, J., Dadonaite, B., Nair, M. S., Mohri, H., Reddem, E. R., Yuan, S., Poon, V. K.-M., Chan, C. C.-S., Yuen, K.-Y., Sheng, Z., Huang, Y., Bloom, J. D., Shapiro, L., Ho, D. D.

10.1101/2023.04.08.536123 — Posted: 2023-04-10

Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors

Harada, T., Perez, M. W., Kalfon, J., Dievenich Braes, F., Batley, R., Eagle, K., Nabet, B., Leifer, B., Kruell, J., Paralkar, V. R., Stegmaier, K., Koehler, A. N., Orkin, S. H., Pimkin, M.

10.1101/2023.04.07.536032 — Posted: 2023-04-07

Stepwise design of pseudosymmetric protein hetero-oligomers

Kibler, R. D., Lee, S., Kennedy, M. A., Wicky, B. I. M., Lai, S. M., Kostelic, M. M., Li, X., Chow, C. M., Carter, L., Wysocki, V. H., Stoddard, B. L., Baker, D.

10.1101/2023.04.07.535760 — Posted: 2023-04-07

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