Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1236 Articles

Clonal interference and changing selective pressures shape the escape of SARS-CoV-2 from hundreds of antibodies

Haddox, H. K., Abdel Aziz, O., Galloway, J. G., Kent, J., Cooper, C. R., Bloom, J. D., Matsen, F. A.

10.1101/2025.01.22.634135 — Posted: 2025-01-24

DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways.

Arends, T., Bennett, S. R., Tapscott, S. J.

10.1101/2024.12.17.628988 — Posted: 2025-01-22

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT

McManus, D., Copsel, S., Pfieffer, B. J., Wolf, D., Barreras, H., Ma, S., Khodor, A., Komai, S., Burgos da Silva, M., Hazime, H., Gallardo, M., van den Brink, M. R., Abreu, M. T., Hill, G. R., Perez, V. L., Levy, R. B.

10.1101/2025.01.16.633453 — Posted: 2025-01-21

A fast numerical integration scheme for clonal expansion processes on graphs

Paterson, C. G. B., Gao, M., Hellier, J., Luebeck, G., Wedge, D. C., Bozic, I.

10.1101/2025.01.13.632690 — Posted: 2025-01-15

Combinatorial phenotypic landscape enables bacterial resistance to phage infection

Gupta, A., Morella, N., Sutormin, D., Li, N., Gaisser, K., Robertson, A., Ispolatov, Y., Seelig, G., Dey, N., Kuchina, A.

10.1101/2025.01.13.632860 — Posted: 2025-01-15

Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics

O'Connor, S. A., Garcia, L., Hoover, R. L., Patel, A. P., Bartelle, B. B., Hugnot, J.-P., PADDISON, P., Plaisier, C. L.

10.1101/2024.04.16.589816 — Posted: 2025-01-15

Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 15-Year Longitudinal Study of 6,986 Women

Pershad, Y., Uddin, M. M., Xue, L., Haessler, J., Collins, J. M., Mack, T. M., Glick, E., Glaser, V., Zhao, K., Jaiswal, S., Manson, J. E., Pandey, U., Desai, P., Natarajan, P., Honigberg, M. C., Kooperberg, C. L., Whitsel, E. A., Kitzman, J., Bick, A. G., Reiner, A. P.

10.1101/2025.01.12.25320422 — Posted: 2025-01-13

The mutation rate of SARS-CoV-2 is highly variable between sites and is influenced by sequence context, genomic region, and RNA structure

Haddox, H. K., Angehrn, G., Sesta, L., Jennings-Shaffer, C., Temple, S. D., Galloway, J. G., DeWitt, W. S., Bloom, J. D., Matsen, F. A., Neher, R. A.

10.1101/2025.01.07.631013 — Posted: 2025-01-08

Metagenomic estimation of absolute bacterial biomass in the mammalian gut through host-derived read normalization.

Tang, G., Carr, A. V., Perez, C., Ramos Sarmiento, K., Levy, L., Lampe, J., Diener, C., Gibbons, S. M.

10.1101/2025.01.07.631807 — Posted: 2025-01-08

Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding

Wang, L., Taylor, T., Rathnakumar, K., Khyzha, N., Liang, M., Alizada, A., Campitelli, L., Pour, S. E., Patel, Z. M., Antounians, L., Tobias, I. C., Hughes, T., Roy, S., Mitchell, J. A., Fish, J. E., Wilson, M. D.

10.1101/2022.10.25.513724 — Posted: 2024-12-30

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