Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1358 Articles

Inflammatory Biomarkers of Asymptomatic and Symptomatic Tuberculosis

Awany, D., Ariefdien, D., Mendelsohn, S., Rozot, V., Mulenga, H., Nyangu, S., Tameris, M., Moloantoa, T., Katona, A., Maruri, F., Noor, F., Panchiar, R., Hlongwane, K., Stanley, K., Van der Heijden, Y., Hadley, K., Fiore-Gartland, A., Innes, C., Brumskine, W., Dheda, K., Jaumdally, S., Perumal, T., Martinson, N., Leslie, A., Fourie, B., Hiemstra, A., Malherbe, S., Walzl, G., Naidoo, K., Churchyard, G., Chegou, N., Sterling, T., Hatherill, M., Scriba, T. J.

10.1101/2025.10.26.684319 — Posted: 2025-10-29

VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials

Williamson, C., Curry, L., Mkhize, N. N., Giorgi, E. E., Magaret, C. A., Lambson, B. E., Bhebhe, S., Kaldine, H., Moyo-Gwete, T., Rolland, M., Rossenkhan, R., Garcia, N. M. G., Moodley, C., Yssel, A., Huang, Y., Marsden, A. A., Reeves, D. B., Mayer, B. T., Bumgarner, R. E., Beaume, N., Westfall, D. H., Juraska, M., DeCamp, A. C., Murrell, H. G., Bai, H., Deng, W., Pankow, A., Bhattacharya, T., York, T., Ndabambi, N., Chen, L., Zhao, H., Gwashu-Nyangiri, A., Thebus, R., Cohen, P., Murrell, B., Karuna, S., Hural, J., Mgodi, N., Edupuganti, S., Morris, L., Montefiori, D., McElrath, M. J., Cohen

10.1101/2025.10.29.685411 — Posted: 2025-10-29

Pre-diagnostic circulating untargeted metabolomics and risk of overall and clinically significant prostate cancer: A systematic review meta-analysis

Fuller, H., Agasaro, O. P., Guevara, J. M., Darst, B. F.

10.1101/2025.02.27.25321444 — Posted: 2025-10-28

Clonal Hematopoiesis and Risk of Stroke: Evidence from Over 800,000 Individuals Across Three Cohorts

Zhao, K., Pershad, Y., Xue, L., Vlasschaert, C., Corty, R. W., Heimlich, J. B., Kooperberg, C., Reiner, A. P., Bick, A. G.

10.1101/2025.10.22.25338594 — Posted: 2025-10-25

Adaptation of the multiplexed CRISPR-Cas13 CARMEN RVP assay for longitudinal detection of respiratory pathogens from air samples

Ellis-Connell, A. L., Stauss, M. R., Barros Tiburcio, P., Emmen, I., Edlefsen, P. T., Kosmider, E., Barlow, S. K., Goss, M. D., Temte, J. L., Stachler, E., McMahon, K., Sabeti, P., O'Connor, D. H., O'Connor, S. L.

10.1101/2025.10.21.25338488 — Posted: 2025-10-23

TGF-β-pathway-based polygenic risk score modifies the association between red meat intake and colorectal cancer risk: Application of a novel pathway-based PRS method

Sanchez Mendez, J., Queme, B., Fu, Y., Morrison, J., Lewinger, J. P., Kawaguchi, E., Mi, H., Obon-Santacana, M., Moratalla-Navarro, F., Martin, V., Moreno, V., Qu, C., Huyghe, J. R., Newcomb, P. A., Phipps, A. I., Thomas, C. E., Conti, D. V., Wang, J., Platz, E. A., Visvanathan, K., Keku, T. O., Newton, C. C., Um, C. Y., Kundaje, A., Gunter, M. J., Dimou, N., Papadimitriou, N., van Duijnhoven, F. J., Männistö, S., Rennert, G., Wolk, A., Hoffmeister, M., Brenner, H., Tian, Y., Le Marchand, L., Bouras, E., Tsilidis, K. K., Bishop, D. T., Maclnnis, R., Buchanan, D., Ulrich, C. M., Peoples, A. R

10.1101/2025.06.13.25329599 — Posted: 2025-10-15

A Flexible and Responsive Remote Study Design to Assess Gene Expression Changes During Wildfire Smoke Exposure with homeRNA, an At-home Blood Sampling Kit

Haack, A. J., Brown, L. G., Zeng, Y., Khan, T., Robertson, I. H., Kennedy, D. S., Adams, K. N., MacDonald, J. W., Bammler, T. K., Stefanovic, F., Moloney, K., Stolarczuk, J. E., Takezawa, M., Alizai, M. Y., Hassan, G. W., Lim, F. Y., Chaussabel, D., Walker, E. G., Errett, N. A., Berthier, E., Theberge, A. B.

10.1101/2025.10.11.25337783 — Posted: 2025-10-14

Moving Beyond Binary Biomarkers: Machine Learning Model Resolves Concurrent and Molecularly Heterogeneous Mismatch Repair and Homologous Recombination Deficiencies in Prostate Cancer

Sharma, K., Wilson, D. A., Wang, Y., Haider, S., Bhatlapenumarthi, V., Boiarsky, D., Cipriaso, J. M., Yermakov, L., Dutta, R., Vashisth, M., Coleman, I. M., Bankhead, A., Jadhav, S. K., Neupane, B., Taylor, B. W., Morrissey, C., Schweitzer, M. T., Montgomery, R. B., Rao, S., Nevalainen, M. T., Nelson, A. A., Antonarakis, E. S., Pilea, P. G., Berchuk, J. E., Zarrabi, K. K., Pritchard, C., Kothari, A., Chen, H.-Z., George, B., Kurzrock, R., Ha, G., Nelson, P. S., Banerjee, A., Auer, P. L., Kilari, D., De Sarkar, N.

10.1101/2025.10.08.680958 — Posted: 2025-10-14

Pervasive suppressors halt the spread of selfish Segregation Distorter in a natural population

Chang, C.-H., Handler, T., Fuda, N., Pascua, D., Mouton, T., Larracuente, A. M.

10.1101/2025.10.13.681989 — Posted: 2025-10-14

A telomere-to-telomere map of somatic mutation burden and functional impact in cancer

Sohn, M.-H., Dubocanin, D., Vollger, M. R., Kwon, Y., Minkina, A., Munson, K. M., Hart, S. F., Ranchalis, J. E., Parmalee, N. L., Sedeno-Cortes, A. E., Ou, J., Au, N. Y., Bohaczuk, S., Carroll, B., Frazar, C. D., Harvey, W. T., Hoekzema, K., Huang, M.-F., Jacques, C. N., Jensen, D. M., Kolar, J. T., Lee, R., Lin, J., Loy, K., Mack, T., Mao, Y., Pham, M. M., Ryke, E., Smith, J. D., Sutherlin, L., Swanson, E. G., Weiss, J. M., SMaHT Assembly Working Group, , Carvalho, C., Coorens, T. H., Harris, K., Wei, C.-L., Eichler, E. E., Altemose, N., Bennett, J. T., Stergachis, A. B.

10.1101/2025.10.10.681725 — Posted: 2025-10-13

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