Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1070 Articles

Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population

Sujatha Jagannathan, Robert K. Bradley

10.1101/038687 — Posted: 2016-09-16

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA

Orr Ashenberg, Jai Padmakumar, Michael B Doud, Jesse Bloom

10.1101/071969 — Posted: 2016-08-28

The validity of pairwise models in predicting community dynamics

Babak Momeni, Li Xie, Wenying Shou

10.1101/060988 — Posted: 2016-08-27

Experimental estimation of the effects of all amino-acid mutations to HIV Env

Hugh K Haddox, Adam S Dingens, Jesse Bloom

10.1101/067470 — Posted: 2016-08-02

Massively parallel digital transcriptional profiling of single cells

Grace X.Y. Zheng, Jessica M Terry, Phillip Belgrader, Paul Ryvkin, Zachary W. Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark T. Gregory, Joe Shuga, Luz Montesclaros, Donald A Masquelier, Stefanie Y. Nishimura, Michael Schnall-Levin, Paul W Wyatt, Christopher M. Hindson, Rajiv Bharadwaj, Alexander Wong, Kevin D. Ness, Lan W. Beppu, Joachim Deeg, Christopher McFarland, Keith R. Loeb, William J. Valente, Nolan G. Ericson, Emily A. Stevens, Jerald P. Radich, Tarjei S. Mikkelsen, Benjamin J. Hindson, Jason H Bielas

10.1101/065912 — Posted: 2016-07-26

Cryopreservation of human mucosal leukocytes

Sean M. Hughes, Zhiquan Shu, Claire N. Levy, April L. Ferre, Heather Hartig, Cifeng Fang, Gretchen Lentz, Michael Fialkow, Anna C Kirby, Kristina M Adams Waldorf, Ronald S Veazey, Anja Germann, Hagen von Briesen, M. Juliana McElrath, Charlene S Dezzutti, Elizabeth Sinclair, Chris A. R. Baker, Barbara L Shacklett, Dayong Gao, Florian Hladik

10.1101/039578 — Posted: 2016-05-18

Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer

Safiye Celik, Benjamin A Logsdon, Stephanie Battle, Charles W Drescher, Mara Rendi, David Hawkins, Su-In Lee

10.1101/048215 — Posted: 2016-04-13

Winners curse correction and variable thresholding improve performance of polygenic risk modeling based on summary-level data from genome-wide association studies

Jianxin Shi, JuHyun Park, Jubao Duan, Sonja Berndt, Winton Moy, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D. Figueroa, Victoria K. Cortessis, Nuria Malats, Margaret R. Karagas, Paolo Vineis, I-Shou Chang, Dongxin Lin, Baosen Zhou, Adeline Seow, Keitaro Matsuo, Yun-Chul Hong, Neil E. Caporaso, Brian Wolpin, Eric Jacobs, Gloria Petersen, Donghui Li, Harvey Risch, Alan R. Sanders, Li Hsu, Robert E. Schoen, Hermann Brenner, Rachael Stolzenberg-Solomon, Pablo Gejman, Qing Lan, Nathaniel Rothman, Laufey T. Amundadottir, Alison P. Klein, Maria Teresa Landi, Douglas F. Levinson, Stephen

10.1101/034082 — Posted: 2016-01-10

Conjecture: Some auto-immune diseases are caused by the tissue, not a problem with the immune system

Harlan S Robins

10.1101/032300 — Posted: 2015-11-20

Immunosequencing reveals diagnostic signatures of chronic viral infection in T cell memory

Ryan Emerson, William DeWitt, Marissa Vignali, Jenna Gravley, Cindy Desmarais, Christoper Carlson, John Hansen, Mark Rieder, Harlan Robins

10.1101/026567 — Posted: 2015-09-11

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