Channel: University of Iowa

This collection includes bioRxiv and medRxiv papers from authors at University of Iowa.

1171 Articles

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R., Paternoster, L., Bradfield, J., Kreiner-Moller, E., Huikari, V., Metrustry, S., Lunetta, K., Painter, J., Hottenga, J.-J., Allard, C., Barton, S., Espinosa, A., Marsh, J., Potter, C., Zhang, G., Ang, W., Berry, D., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, O., Hocher, B., Hofman, A., Inskip, H., Jones, S. E., Kogevinas, M., Lind, P., Marullo, L., Medland, S., Murray, A., Murray, J., Njolstad, P. R., Nohr, E., Reichetzeder, C., Ring, S., Ruth

10.1101/034207 — Posted: 2017-09-08

Systematic integration of biomedical knowledge prioritizes drugs for repurposing

Himmelstein, D. S., Lizee, A., Hessler, C., Brueggeman, L., Chen, S. L., Hadley, D., Green, A., Khankhanian, P., Baranzini, S. E.

10.1101/087619 — Posted: 2017-08-31

Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain

Shepherd, A. J., Mickle, A. D., Copits, B. A., Karlsson, P., Kadunganattil, S., Golden, J. P., Tadinada, S. M., Mack, M. R., Haroutounian, S., de Kloet, A. D., Samineni, V. K., Valtcheva, M. V., McIlvried, L. A., Sheahan, T. D., Jain, S., Ray, P. R., Usachev, Y. M., Dussor, G., Kim, B. S., Krause, E. G., Price, T. J., Gereau, R. W., Mohapatra, D. P.

10.1101/166546 — Posted: 2017-08-30

TiSAn: Estimating Tissue Specific Effects of Coding and Non-coding Variants

Vervier, K., Michaelson, J. J.

10.1101/141408 — Posted: 2017-08-30

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V., Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivieres, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Renteria, M. E., Kim, S., Hohn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roi

10.1101/173831 — Posted: 2017-08-28

The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age

Szecsenyi-Nagy, A., Roth, C., Brandt, G., Rihuete-Herrada, C., Tejedor-Rodriguez, C., Held, P., Garcia-Martinez-de-Lagran, I., Arcusa Magallon, H., Zesch, S., Knipper, C., Banffy, E., Friedrich, S., Meller, H., Bueno-Ramirez, P., Barroso Bermejo, R., de Balbin Behrmann, R., Herrero-Coral, A. M., Flores Fernandez, R., Alonso Fernandez, C., Jimenez Echevarria, J., Rindlisbacher, L., Oliart, C., Fregeiro, M.-I., Soriano, I., Vincente, O., Mico, R., Lull, V., Soler Diaz, J., Lopez Padilla, J. A., Roca de Togores Munoz, C., Hernandez Perez, M. S., Jover Maestre, F. J., Lomba Maurandi, J., Aviles Fe

10.1101/106963 — Posted: 2017-08-21

The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site

Zhang, L., Rube, H. T., Bussemaker, H. J., Pufall, M. A.

10.1101/176255 — Posted: 2017-08-15

SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

Zhang, L., Martini, G., Rube, H. T., Kribelbauer, J. F., Rastogi, C., FitzPatrick, V. D., Houtman, J. C., Bussemaker, H. J., Pufall, M. A.

10.1101/176073 — Posted: 2017-08-14

Olfactory learning primes the heat shock transcription factor HSF-1 to enhance the expression of molecular chaperone genes in C. elegans

Ooi, F. K., Prahlad, V.

10.1101/152736 — Posted: 2017-08-08

Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

Martin-Galvez, D., Dunoyer de Segonzac, D., Ma, M. C. J., Kwitek, A. E., Thybert, D., Flicek, P.

10.1101/169748 — Posted: 2017-07-29

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