Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2708 Articles

A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading

Bloks, N. G. C., Harissa, Z., Adkar, S. S., Dicks, A., Hajmousa, G., Steward, N., Koning, R. I., Mulder, A., de Koning, B. B. R., Kloppenburg, M., Coutinho de Almeida, R., Ramos, Y. F. M., Guilak, F., Meulenbelt, I.

10.1101/2022.12.19.520461 — Posted: 2023-04-05

Acute kidney injury-induced circulating TNFR1/2 elevations correlate with persistent kidney injury and progression to fibrosis

Arthanarisami, A., Komaru, Y., Katsouridi, C., Schumacher, J., Verges, D. K., Ning, L., Abdelmageed, M. M., Herrlich, A., Kefaloyianni, E.

10.1101/2023.04.03.534558 — Posted: 2023-04-04

Human gut bacteria tailor extracellular vesicle cargo for the breakdown of diet- and host-derived glycans

Sartorio, M. G., Pardue, E. J., Scott, N. E., Feldman, M. F.

10.1101/2023.04.03.535451 — Posted: 2023-04-03

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons

Yi, J., Bertels, Z., Del Rosario, J. S., Widman, A. J., Slivicki, R. A., Payne, M., Susser, H. M., Copits, B. A., Gereau, R. W.

10.1101/2023.03.31.534820 — Posted: 2023-04-01

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Rayner, N. W., Bocher, O., de S. V. Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B., Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J.-J., Pan, I., Taliun, D., Parra, E. J., Chai, J.-F., Bielak, L. F., Tabara, Y., Hai, Y., Thorleifsson, G., Grarup, N., Sofer, T., Wuttke, M., Sarnowski, C., Gie

10.1101/2023.03.31.23287839 — Posted: 2023-03-31

Immunogenicity of the BA.1 and BA.4/5 Bivalent Boosts: A Brief Report of Preliminary Results from the COVAIL Randomized Clinical Trial

Branche, A. R., Rouphael, N., Losada, C., Baden, L. R., Anderson, E. J., Luetkemeyer, A. F., Diemert, D. J., Winokur, P. L., Presti, R. M., Kottkamp, A. C., Falsey, A. R., Frey, S. E., Rupp, R., Backer, M., Novak, R. M., Walter, E. B., Jackson, L. A., Little, S. J., Immergluck, L. C., Mahgoub, S. M., Whitaker, J. A., Babu, T. M., Goepfert, P. A., Fusco, D. N., Atmar, R. L., Posavad, C. M., Netzl, A., Smith, D. J., Telu, K., Mu, J., Matkowski, M., Makhene, M., Crandon, S., Montefiori, D. C., Roberts, P. C., Beigel, J. H.

10.1101/2023.01.31.23285306 — Posted: 2023-03-31

Enhanced selectivity of transcutaneous spinal cord stimulation by multielectrode configuration

Bryson, N. K., Lombardi, L., Hawthorn, R., Fei, J., Keesey, R., Peiffer, J. D., Seanez, I.

10.1101/2023.03.30.534835 — Posted: 2023-03-31

Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

Freshour, S. L., Chen, T. H.-P., Fisk, B., Shen, H., Mosior, M., Skidmore, Z. L., Fronick, C., Bolzenius, J. K., Griffith, O. L., Arora, V. K., Griffith, M.

10.1101/2023.03.28.534561 — Posted: 2023-03-29

NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype

Muela-Zarzuela, I., Suarez-Rivero, J. M., Gallardo-Orihuela, A., Wang, C., Izawa, K., de Gregorio-Procopio, M., Couillin, I., Ryffel, B., Kitaura, J., Sanz, A., von Zglinicki, T., Mbalaviele, G., Cordero, M. D.

10.1101/2023.02.06.527254 — Posted: 2023-03-28

Interpretable spatial cell learning enhances the characterization of patient tissue microenvironments with highly multiplexed imaging data

Lu, P., Oetjen, K., Oh, S., Thorek, D. L.

10.1101/2023.03.26.534306 — Posted: 2023-03-28

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