Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

3602 Articles

Bifunctional transcriptional effector domains control gene expression pulses in an occupancy-dependent manner

Andrews, C. J., Costa, E. J., Janer Carattini, G. L., DelRosso, N. V., Fujimori, T., Shimasawa, M., Bintu, L.

10.64898/2025.12.10.693551 — Posted: 2025-12-12

BCGNet: An AI Model Trained on 600K Hours of Sleep Data for a Novel Under-Pillow Contactless Monitoring Device

Chen, S., Chen, X., Huang, W., Lei, F., Shan, C., Jin, Z., Shi, Y., Wang, Y., Zhao, R., Xu, X., Lv, D., Li, Y., Pan, S., Chiang, A., Westover, B., Hong, S., Zhang, C., Yin, S., Liu, C.-f., Yi, H., Tang, X., Leng, Y.

10.1101/2025.08.23.25334218 — Posted: 2025-12-12

Alveolar Type II Cell-derived MMP1high basal cells promote destructive microcysts in idiopathic pulmonary fibrosis.

Garakani, K., Brumwell, A. N., Toigo, M., Jacob, A., Wei, Y., Ho, T. C., Wolters, P., Matthay, M. A., Volk, R. F., Zaro, B. W., Iantorno, S. A., Berhan, A., Sheppard, D. W., Auyeung, V. C., Jourdan Le Saux, C. C., Chapman, H. A.

10.64898/2025.12.08.693033 — Posted: 2025-12-11

Activation of cannabinoid receptor CB1 leads to aberrant myelination in development

Miramontes, T. G., Hamling, K. R., Doan, R. A., Singh, S., Collins, H. Y., Emery, B., Call, C. L., Monk, K.

10.64898/2025.12.10.693544 — Posted: 2025-12-11

Targeting p16INK4a reverses alveolar epithelial cell dysfunction and induces lung regeneration in emphysema

Ribeiro Baptista, B., Toigo, M., Justeau, G., Abou-atmeh, P., De Freitas Castro, T., Zysman, M., Thiebaut De Menonville, C., Audureau, E., Schnyder, K., Wang, H., Hu, Y., Koenigshoff, M., Lanone, S., Chabot, F., Zana-Taieb, E., Jourdan Le Saux, C., Lehmann, M., Thuret, J.-Y., Derumeaux, G., Boczkowski, J., Gote-Schniering, J., Boyer, L.

10.1101/2025.09.05.674489 — Posted: 2025-12-11

Clinical and imaging characteristics of Parkinson's disease with negative alpha-synuclein seed amplification assay

Brooker, S. M., Pasquini, J., Choi, S. H., Lafontant, D.-E., Fereshtehnejad, S.-M., Zeighami, Y., Grillo, P., Riboldi, G. M., Azizi, H., Moqadam, R., Kang, U. J., Nudelman, K. N. H., Siderowf, A., Tanner, C. M., Tropea, T. F., Foroud, T., Chahine, L. M., Mollenhauer, B., Merchant, K. M., Galasko, D., Coffey, C. S., Dobkin, R. D., Brown, E. G., Alcalay, R. N., Weintraub, D., Marek, K., Simuni, T., Latapi, P. G., Pavese, N., Poston, K. L.

10.1101/2025.10.01.25337085 — Posted: 2025-12-10

Allele Frequencies at Recessive Disease Genes are Mainly Determined by Pleiotropic Effects in Heterozygotes

Judd, J., Spence, J. P., Milind, N., Kachuri, L., Witte, J. S., Pritchard, J. K.

10.64898/2025.12.05.692665 — Posted: 2025-12-09

A Transcriptomics-Based Computational Drug Repurposing Pipeline Identifies Simvastatin And Primaquine As Therapeutics For Endometriosis

Oskotsky, T. T., Tang, X., Arthurs, E., Govil, A., Abbasi, F., Bhoja, A., Bunis, D. J., Lau, A., Einhaus, J., Diop, M., Irwin, J. C., Gaudilliere, B., Stevenson, D. K., Giudice, L. C., McAllister, S. L., Sirota, M.

10.1101/2025.05.28.656743 — Posted: 2025-12-09

Neuronal APOE4 drives damaging lipid accumulation via contact-dependent neuron-oligodendrocyte-microglia interaction in Alzheimer's disease

Kim, M. J., Blumenfeld, J., Li, Y., Yip, O., Yao, L., Ancheta, S., De Leon, S., Platow, Z., Liang, Z., Shostak, D., Suan, K., Hao, Y., Koutsodendris, N., Ellis, C., Nguyen, J., Huang, Y.

10.64898/2025.12.04.692390 — Posted: 2025-12-09

Tri-AD: Hippocampal cell-type-specific responses to age, sex and APOE genotype

Li, Y., Li, Y., Pereda Serras, C., Yao, L., Liang, Z., Almonte-Loya, A., Blumenfeld, J., Suan, K., Yoon, S. Y., Grone, B., Ding, L., Ma, Y., Sun, S., Oskotsky, B., Oskotsky, T., Condello, C., Huang, Y., Sirota, M.

10.64898/2025.12.03.691944 — Posted: 2025-12-08

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