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A systematic CRISPR screen reveals an IL-20/IL20RA-mediated peritoneal immune crosstalk to prevent the ovarian cancer metastasis

Li, J., Qin, X., Shi, J., Wang, X., Li, T., Xu, M., Chen, X., Zhao, Y., Han, J., Piao, Y., Zhang, W., Qu, P., Wang, L., Xiang, R., Shi, Y.

10.1101/2021.01.03.425154 — Posted: 2021-01-04 — Discussion: 2021-03-18 eLife

Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception

Yang, S., Zhang, Y., Yang, C., Wu, X., El Oud, S. M., Chen, R., Cai, X., Wu, X., Lan, G., Zheng, X.

10.1101/2021.02.19.432013 — Posted: 2021-02-20 — Discussion: 2021-03-18 eLife

Intra and inter-annual climatic conditions have stronger effect than grazing intensity on root growth of permanent grasslands

Picon-Cochard, C., Vassal, N., Martin, R., Herfurth, D., Note, P., Louault, F.

10.1101/2020.08.23.263137 — Posted: 2020-08-24 — Discussion: 2021-03-17 Peer Community In

Expansion of CD14+HLA-DRneg/low monocytes and CD10neg neutrophils driving proinflammatory responses in patients with acute myocardial infarction

Fraccarollo, D., Neuser, J., Moeller, J., Galuppo, P., Bauersachs, J.

10.1101/2020.09.21.306118 — Posted: 2020-09-21 — Discussion: 2021-03-17 eLife

Allosteric communication in Class A β-lactamases occurs via Cooperative Coupling of Loop Dynamics

Galdadas, I., Qu, S., Oliveira, A. S. F., Olehnovics, E., Mack, A. R., Mojica, M. F., Agarwal, P. K., Tooke, C. L., Gervasio, F. L., Spencer, J., Bonomo, R. A., Mulholland, A. J., Haider, S.

10.1101/2020.12.30.424904 — Posted: 2021-01-01 — Discussion: 2021-03-17 eLife

TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 NPC subcomplex via phosphorylation of RanGAP1 by PKC-θ

Li, Y., He, Y., Yang, Z., Zhao, C.-s., Gong, Y., Xiao, Z., Li, Y.-y., Chen, Y., Feng, D., Altman, A.

10.1101/2021.03.10.434793 — Posted: 2021-03-10 — Discussion: 2021-03-17 eLife

Genetic integration of the stress response

Houslay, T. M., Earley, R. L., White, S. J., Lammers, W., Grimmer, A. J., Travers, L., Johnson, E., Young, A. J., Wilson, A. J.

10.1101/770586 — Posted: 2019-09-16 — Discussion: 2021-03-17 eLife

Asymptomatic Bordetella pertussis infections in young African infants and their mothers identified within a longitudinal cohort

Gill, C., Gunning, C. E., Macleod, W. B., Mwananyanda, L., Thea, D. M., Pieciak, R. C., Kwenda, G., Mupila, Z., Rohani, P.

10.1101/2020.11.18.20231423 — Posted: 2020-11-19 — Discussion: 2021-03-17 eLife

Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2

Xie, Y., Clarke, B. P., Kim, Y. J., Ivey, A. L., Hill, P. S., Shi, Y., Ren, Y.

10.1101/2021.01.04.425184 — Posted: 2021-01-04 — Discussion: 2021-03-16 eLife

Distinct spermiogenic phenotypes underlie sperm elimination in the Segregation Distorter meiotic drive system

Herbette, M., Wei, X., Chang, C.-H., Larracuente, A. M., Loppin, B., Dubruille, R.

10.1101/2021.01.08.425928 — Posted: 2021-01-09 — Discussion: 2021-03-16 Review Commons