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Nuclear Hormone Receptor NHR-49 controls a HIF-1-independent hypoxia adaptation pathway in Caenorhabditis elegans
Doering, K. R. S., Cheng, X., Milburn, L., Ratnappan, R., Ghazi, A., Miller, D. L., Taubert, S.
10.1101/2021.02.24.432575 — Posted: 2021-02-24 — Discussion: 2022-02-04  eLife
Genetically engineered insects with sex-selection and genetic incompatibility enable population suppression
Upadhyay, A., Feltman, N., Sychla, A., Das, S., Maselko, M., Smanski, M.
10.1101/2021.06.11.448100 — Posted: 2021-06-11 — Discussion: 2022-02-04  eLife
Cis-Regulatory Hubs: a Relevant 3D Model to Study the Genetics of Complex Diseases with an Application to Schizophrenia
Mangnier, L., Joly-Beauparlant, C., Droit, A., Bilodeau, S., Bureau, A.
10.1101/2021.06.22.449467 — Posted: 2021-06-22 — Discussion: 2022-02-04  EMBO Press
LRET-derived HADDOCK structural models describe the conformational heterogeneity required for processivity of the Mre11-Rad50 DNA damage repair complex
Canny, M. D., Latham, M.
10.1101/2021.08.04.455035 — Posted: 2021-08-04 — Discussion: 2022-02-04  eLife
Role of YAP in early ectodermal specification anda Huntington's Disease model of human neurulation
Piccolo, F. M., Kastan, N. R., Haremaki, T., Tian, Q., Laundos, T. L., De Santis, R., Carroll, T. S., Luo, J.-D., Gnedeva, K., Etoc, F., Hudspeth, A. J., Brivanlou, A. H.
10.1101/2021.08.11.455964 — Posted: 2021-08-11 — Discussion: 2022-02-04  eLife
Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting
Reck, J. R., Beuret, N., Demirci, E., Prescianotto-Baschong, C., Spiess, M.
10.1101/2021.08.20.457087 — Posted: 2021-08-20 — Discussion: 2022-02-04  EMBO Press
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia
Jairaman, A., McQuade, A., Kang, Y. J., Granzotto, A., Chadarevian, J. P., Gandhi, S., Parker, I., Smith, I., Othy, S., Cho, H., Blurton-Jones, M., Cahalan, M. D.
10.1101/2021.08.24.457491 — Posted: 2021-08-24 — Discussion: 2022-02-04  eLife
Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader
Gaubitz, C., Liu, X., Pajak, J., Stone, N. P., Hayes, J. A., Demo, G., Kelch, B. A.
10.1101/2021.09.23.461575 — Posted: 2021-09-23 — Discussion: 2022-02-04  eLife
Maintenance of copy number variation at the human salivary agglutinin gene (DMBT1) by balancing selection driven by host-microbe interactions
Alharbi, A., Sheng, N., Nicol, K., Strömberg, N., Hollox, E.
10.1101/2021.10.29.466477 — Posted: 2021-10-30 — Discussion: 2022-02-04  PeerRef BioMed
Structural Basis for an Unprecedented Enzymatic Alkylation in Cylindrocyclophane Biosynthesis
Braffman, N. R., Ruskoski, T. B., Davis, K. M., Glasser, N. R., Johnson, C., Okafor, D., Boal, A. K., Balskus, E. P.
10.1101/2021.12.02.470901 — Posted: 2021-12-02 — Discussion: 2022-02-04  eLife

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