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7,584 Reviews — eLife — All Subjects

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Artificial Intelligence uncovers Evolutionarily Conserved Intracellular Allosteric Modulators of GPCR-Gα interface.
Mohanty, S. K., Mittal, A., Gaur, A., Solanki, S., Kumar, S., Duari, S., Arora, S., Gautam, V., Dixit, N. K., Ghosh, T. S., Sengupta, D., Gupta, S. K., Murugan, N. A., Ahuja, G.
10.1101/2023.02.14.528587 — Posted: 2023-02-15 — Discussion: 2025-05-23  eLife
Exosome-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and Glucocerebrosidase activity
Meneses-Salas, E., Arnold, M., Hsieh, F., Enrich, C., Pfeffer, S. R., Merchant, K. M., Lu, A.
10.1101/2023.07.12.548710 — Posted: 2023-07-13 — Discussion: 2025-05-23  eLife
PI3Kalpha inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
Valer, J. A., Deber, A., Wits, M., Pimenta, C., Goumans, M. J., Rosa, J. L., Sanchez-Duffhues, G., Ventura, F.
10.1101/2023.09.14.557704 — Posted: 2023-09-14 — Discussion: 2025-05-23  eLife
Predicting the effect of CRISPR-Cas9-based epigenome editing
Batra, S. S., Cabrera, A., Spence, J. P., Hilton, I., Song, Y. S.
10.1101/2023.10.03.560674 — Posted: 2023-10-03 — Discussion: 2025-05-23  eLife
p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
Brdar, A., Osterburg, C., Münick, P., Machel, A. C., Rathore, R., Osterburg, S., Yüksel, B., Schäfer, B., Desch, K., Langer, J. D., Dikic, I., Dötsch, V.
10.1101/2024.10.02.616239 — Posted: 2024-10-06 — Discussion: 2025-05-23  eLife
Neocortical Layer-5 tLTD Relies on Non-Ionotropic Presynaptic NMDA Receptor Signaling
Thomazeau, A., Rannio, S., Brock, J. A., Wong, H. H.-W., Sjöström, P. J.
10.1101/2025.02.07.637179 — Posted: 2025-02-10 — Discussion: 2025-05-23  eLife
Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease
Graff, M. F. E., Heeg, E. E., Childs, S. J.
10.1101/2025.03.13.643043 — Posted: 2025-03-13 — Discussion: 2025-05-23  eLife
GMCL1 Controls 53BP1 Stability and Modulates Paclitaxel Sensitivity in Cancer
KITO, Y., Gonzalez-Robles, T. J., Kaisari, S., Pae, J., Garcia, S. F., Ortiz-Pacheco, J., Ueberheide, B., Lehmann, R., Marzio, A., Rona, G., Pagano, M.
10.1101/2025.03.18.643855 — Posted: 2025-03-20 — Discussion: 2025-05-23  eLife
The ESCRT protein CHMP5 restrains skeletal progenitor cell senescence by preserving endo-lysosomal-mitochondrial network
Ge, X., He, L., Liu, H., Haynes, C. M., Shim, J.-H.
10.1101/2020.08.03.233874 — Posted: 2020-08-04 — Discussion: 2025-05-22  eLife
Somatic hypermutation spectra are independent of the local transcriptional and epigenetic landscape
Schoeberl, U. E., Fitz, J., Froussios, K., Valieris, R., Makharova, M., Ourailidis, I., Bauer, B., Neumann, T., Wiedemann, E.-M., Steininger, M., Garcia, A. C., Mastrovito, M., Mouquet, H., Silva, I., Pavri, R.
10.1101/2022.05.21.492925 — Posted: 2022-05-21 — Discussion: 2025-05-22  eLife

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