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Genome-scale metabolic modeling reveals SARS-CoV-2-induced host metabolic reprogramming and identifies metabolic antiviral targets
Cheng, K., Riva, L., Sinha, S., Pal, L. R., Nair, N. U., Martin-Sancho, L., Chanda, S. K., Ruppin, E.
10.1101/2021.01.27.428543 — Posted: 2021-01-28 — Discussion: 2021-12-01  EMBO Press
Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference
Lynch, A. R., Arp, N. L., Zhou, A. S., Weaver, B. A., Burkard, M. E.
10.1101/2021.04.26.441466 — Posted: 2021-04-27 — Discussion: 2021-12-01  eLife
Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein
Glon, D., Vilmen, G., Perdiz, D., Hernandez, E., Beauclair, G., Maréchal, V., Poüs, C., Lussignol, M., Esclatine, A.
10.1101/2021.06.11.448012 — Posted: 2021-06-11 — Discussion: 2021-12-01  Review Commons
Navigating a diversity of turbulent plumes is enhanced by sensing complementary temporal features of odor signals
Jayaram, V., Kadakia, N., Emonet, T.
10.1101/2021.07.28.454116 — Posted: 2021-07-28 — Discussion: 2021-12-01  eLife
Stereo-specific Lasofoxifene Derivatives Reveal the Interplay between Estrogen Receptor Alpha Stability and Antagonistic Activity in ESR1 Mutant Breast Cancer Cells
Hosfield, D. J., Weber, S., Li, N.-S., Suavage, M., Sullivan, E., Nduwke, E., Han, R., Cush, S., Laine, M., Mader, S. C., Greene, G. L., Fanning, S. W.
10.1101/2021.08.27.457901 — Posted: 2021-08-28 — Discussion: 2021-12-01  eLife
Allosteric modulation of the adenosine A2A receptor by cholesterol
Huang, S. K., Almurad, O., Pejana, R. J., Morrison, Z. A., Pandey, A., Picard, L.-P., Nitz, M., Sljoka, A., Prosser, R. S.
10.1101/2021.09.13.460151 — Posted: 2021-09-14 — Discussion: 2021-12-01  eLife
A Helicase-tethered ORC Flip Enables Bidirectional Helicase Loading
Gupta, S., Friedman, L. J., Gelles, J., Bell, S. P.
10.1101/2021.10.06.463322 — Posted: 2021-10-06 — Discussion: 2021-12-01  eLife
Molecular pathology of a cystic fibrosis mutation is explained by loss of a hydrogen bond
Simon, M. A., Csanady, L.
10.1101/2021.10.19.464938 — Posted: 2021-10-21 — Discussion: 2021-12-01  eLife
Label-free imaging of macrophage phenotypes and phagocytic activity in the human dermis in vivo using two-photon excited FLIM
Kröger, M., Scheffel, J., Shirshin, E. A., Schleusener, J., Meinke, M. C., Lademann, J., Maurer, M., Darvin, M.
10.1101/2021.11.29.470361 — Posted: 2021-11-30 — Discussion: 2021-12-01  eLife
Establishment of Developmental Gene Silencing by Ordered Polycomb Complex Recruitment in Early Zebrafish Embryos
Cairns, B. R., Hickey, G. J. M., Wike, C., Nie, X., Guo, Y., Murphy, P. J., Tan, M.
10.1101/2021.03.16.435592 — Posted: 2021-03-16 — Discussion: 2021-11-30  eLife

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