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A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with progressive motor and cognitive decline
Weiss, A. R., Liguore, W. A., Brandon, K., Wang, X., Liu, Z., Domire, J. S., Button, D., Kroenke, C. D., McBride, J. L.
10.1101/2022.02.02.478920 — Posted: 2022-02-04 — Discussion: 2022-08-16  eLife
Botulinum neurotoxin accurately separates tonic vs phasic transmission and reveals heterosynaptic plasticity rules in Drosophila
Han, Y., Chien, C., Goel, P., He, K., Pinales, C., Buser, C., Dickman, D.
10.1101/2022.02.15.480429 — Posted: 2022-02-17 — Discussion: 2022-08-16  eLife
Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
Monterisi, S., Michl, J., Hill, A. E., Hulikova, A., Abdullayeva, G., Bodmer, W. F., Swietach, P.
10.1101/2022.03.15.484462 — Posted: 2022-03-16 — Discussion: 2022-08-16  eLife
A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
Zhang, J., Han, Z. B., Liang, Y., Zhang, X. F., Jin, Y. Q., Du, L. F., Shao, S., Wang, H., Hou, J. W., Xu, K., Lei, Z. H., Liu, Z. M., Zhang, J., Hou, Y. N., Liu, N., Shen, F. J., Wu, J. J., Zheng, X., Li, X. Y., Li, X., Huang, W. J., Wu, G. Z., Su, J. G., Li, Q. M.
10.1101/2022.03.29.486173 — Posted: 2022-03-29 — Discussion: 2022-08-16  eLife
eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways
Ahmed, I., Yang, S.-H., Ogden, S., Li, Y., Zhang, W., the OCCAMs consortium, , Sharrocks, A.
10.1101/2022.05.11.491502 — Posted: 2022-05-11 — Discussion: 2022-08-16  eLife
Distinct architectural requirements for the parS centromeric sequence of the pSM19035 plasmid partition machinery
Volante, A., Alonso, J. C., Mizuuchi, K.
10.1101/2022.05.29.493902 — Posted: 2022-05-30 — Discussion: 2022-08-16  eLife
Neither kin selection nor familiarity explain affiliative biases towards maternal siblings in wild mountain gorillas
Grebe, N., Hirwa, J. P., Stoinski, T. S., Vigilant, L., Rosenbaum, S.
10.1101/2022.06.14.496042 — Posted: 2022-06-16 — Discussion: 2022-08-16  eLife
Rodent perirhinal cortex, but not ventral hippocampus, inhibition induces approach bias under object-based approach-avoidance conflict
Dhawan, S. S., Pinter, C., Lee, A. C., Ito, R.
10.1101/2022.06.28.497792 — Posted: 2022-07-02 — Discussion: 2022-08-16  eLife
An atlas of associations between polygenic risk scores from across the human phenome and circulating metabolic biomarkers
Fang, S., Holmes, M. V., Gaunt, T. R., Davey Smith, G., Richardson, T. G.
10.1101/2021.10.14.21265005 — Posted: 2021-10-25 — Discussion: 2022-08-16  eLife
Exploratory data on the clinical efficacy of monoclonal antibodies against SARS-CoV-2 Omicron Variant of Concern
Mazzaferri, F., Mirandola, M., Savoldi, A., De Nardo, P., Morra, M., Tebon, M., Armellini, M., De Luca, G., Calandrino, L., Sasset, L., D'Elia, D., Sozio, E., Danese, E., Gibellini, D., Monne, I., Scroccaro, G., Magrini, N., Cattelan, A., Tascini, C., MANTICO Working Group, , Tacconelli, E.
10.1101/2022.05.06.22274613 — Posted: 2022-05-09 — Discussion: 2022-08-16  eLife

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