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The Structure-Selective Endonucleases GEN1 and MUS81 are Functionally Complementary in Safeguarding the Genome of Proliferating B Lymphocytes
Fernandez, K. C., Feeney, L., Smolkin, R. M., Matthews, A. J., Yen, W.-F., Chaudhuri, J., Petrini, J.
10.1101/2022.02.09.479711 — Posted: 2022-02-10 — Discussion: 2022-08-17  eLife
In situ single particle classification reveals distinct 60S maturation intermediates in cells
Lucas, B. A., Zhang, K., Loerch, S., Grigorieff, N.
10.1101/2022.04.10.487797 — Posted: 2022-04-10 — Discussion: 2022-08-17  eLife
Dual mode of PGRP-LE-dependent NF-κB pathway activation in bacteria infected guts
Joshi, M., Viallat-Lieutaud, A., Royet, J.
10.1101/2022.05.04.490610 — Posted: 2022-05-04 — Discussion: 2022-08-17  Review Commons
Trapped pore waters in the open proton channel HV1
Boytsov, D., Brescia, S., Chaves, G., Hannesschlaeger, C., Siligan, C., Goessweiner-Mohr, N., Musset, B., Pohl, P.
10.1101/2022.05.09.491141 — Posted: 2022-05-10 — Discussion: 2022-08-17  Review Commons
Time-Encoding Migrates from Prefrontal Cortex to Dorsal Striatum During Learning of a Self-Timed Response Duration Task
Chiuffa Tunes, G., de Oliveira, E. F., Vieira, E. U. P., Caetano, M. S., Cravo, A. M., Reyes, M. B.
10.1101/2020.11.19.390286 — Posted: 2020-11-20 — Discussion: 2022-08-16  eLife
Mechanisms Governing Target Search and Binding Dynamics of Hypoxia-Inducible Factors
Chen, Y., Cattoglio, C., Dailey, G., Zhu, Q., Tjian, R., Darzacq, X.
10.1101/2021.10.27.466110 — Posted: 2021-10-28 — Discussion: 2022-08-16  eLife
Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice
Szego, E. M., Malz, L., Bernhardt, N., Roesen-Wolff, A., Falkenburger, B. H., Luksch, H.
10.1101/2022.02.02.478854 — Posted: 2022-02-04 — Discussion: 2022-08-16  Review Commons
A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with progressive motor and cognitive decline
Weiss, A. R., Liguore, W. A., Brandon, K., Wang, X., Liu, Z., Domire, J. S., Button, D., Kroenke, C. D., McBride, J. L.
10.1101/2022.02.02.478920 — Posted: 2022-02-04 — Discussion: 2022-08-16  eLife
Botulinum neurotoxin accurately separates tonic vs phasic transmission and reveals heterosynaptic plasticity rules in Drosophila
Han, Y., Chien, C., Goel, P., He, K., Pinales, C., Buser, C., Dickman, D.
10.1101/2022.02.15.480429 — Posted: 2022-02-17 — Discussion: 2022-08-16  eLife
Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
Monterisi, S., Michl, J., Hill, A. E., Hulikova, A., Abdullayeva, G., Bodmer, W. F., Swietach, P.
10.1101/2022.03.15.484462 — Posted: 2022-03-16 — Discussion: 2022-08-16  eLife

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