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8,027 Reviews — eLife — All Subjects

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Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease
Howard, C. J., Abell, N. S., Warneford-Thomson, R. R., Mahdavi, E., Su, A. L., Resnick, C., Mohammed, N., Thompson, E. M., Holzinger, E. R., Catalano, K., Hukku, A., Mintier, G. A., Wilson, S. C., Maranville, J. C., Sheth, P. R., Plenge, R. M., Kosuri, S., Dickel, D. E.
10.1101/2025.10.11.681520 — Posted: 2025-10-12 — Discussion: 2026-03-18  eLife
Policy-Gradient Reinforcement Learning as a General Theory of Practice-Based Motor Skill Learning
Haith, A. M.
10.1101/2025.10.17.682587 — Posted: 2025-10-20 — Discussion: 2026-03-18  eLife
Latent gene network expression underlies the reversion of a polyphenic trait in the worker caste of ants
Vasquez-Correa, A., Arnet, J., Chen, T., Abouheif, E.
10.1101/2025.11.19.689334 — Posted: 2025-11-20 — Discussion: 2026-03-18  eLife
Turning aging cells into a live vaccine: engineered senescent cancer cells with adjuvant celecoxib for immunotherapy
Huang, Y., Wang, Y., Ou, A., Gao, Y., Zhang, Y., Qin, L.
10.64898/2025.12.15.694320 — Posted: 2025-12-17 — Discussion: 2026-03-18  eLife
Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens
Kim, J., Correy, G. J., Hall, B. W., Rachman, M. M., Mailhot, O., Togo, T., Gonciarz, R. L., Jaishankar, P., Neitz, R. J., Hantz, E. R., Doruk, Y. U., Stevens, M. G. V., Diolaiti, M. E., Reid, R., Gopalkrishnan, S., Krogan, N. J., Renslo, A. R., Ashworth, A., Shoichet, B. K., Fraser, J. S.
10.64898/2025.12.25.696505 — Posted: 2025-12-28 — Discussion: 2026-03-18  eLife
The targeted cytosolic degradation of class I histone deacetylases is essential for efficient alphaherpesvirus replication
Ming, S., Du, M.-H., Yang, J.-M., Guo, Y.-D., Pan, J.-J., Lu, W.-F., Wang, J., Zeng, L., Chu, B.-B.
10.64898/2026.01.02.697337 — Posted: 2026-01-02 — Discussion: 2026-03-18  eLife
Phosphorylation of KIN-G motor domain by Polo-like kinase negatively regulates centrin arm biogenesis in Trypanosoma brucei
Kurasawa, Y., Zhou, Q., Lee, K. J., Hu, H., Li, Z.
10.64898/2026.01.16.699953 — Posted: 2026-01-17 — Discussion: 2026-03-18  eLife
Expression of specific var gene subtypes is differentially associated with severe malaria syndromes
Ndugwa, H., Muthui, M., Rowe, A., Kinyanjui, S., Andisi, C., Abdi, A. I.
10.64898/2026.02.02.26345432 — Posted: 2026-02-04 — Discussion: 2026-03-18  eLife
No evidence for disassortative mating based on HLA genotype in a natural fertility population
Meeks, G. L., Scelza, B., Kichula, K. M., Berevoescu, C., Hardy, K., Farias, T. D., Harrison, G. F., Pollock, N. R., Font-Porterias, N., Prall, S., Norman, P. J., Henn, B. M.
10.1101/2025.05.06.652536 — Posted: 2025-05-08 — Discussion: 2026-03-17  eLife
How individual vigor shapes human-human physical interaction
Verdel, D., Berret, B., Burdet, E.
10.1101/2025.06.01.657232 — Posted: 2025-06-03 — Discussion: 2026-03-17  eLife

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