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Revisiting the Hayflick Limit: Insights from an Integrated Analysis of Changing Transcripts, Proteins, Metabolites and Chromatin
Chan, M., Yuan, H., Soifer, I., Maile, T. M., Wang, R. Y., Ireland, A., O'Brien, J., Goudeau, J., Chan, L., Vijay, T., Freund, A., Kenyon, C., Bennett, B., McAllister, F., Kelley, D. R., Roy, M., Cohen, R. L., Levinson, A. D., Botstein, D., Hendrickson, D.
10.1101/2021.05.03.442497 — Posted: 2021-05-04 — Discussion: 2021-11-17  eLife
Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs
Atze, H., Rusconi, F., Arthur, M.
10.1101/2021.08.06.454924 — Posted: 2021-08-06 — Discussion: 2021-11-17  eLife
Mg2+-dependent conformational equilibria in CorA: an integrated view on transport regulation
Johansen, N. T., Bonaccorsi, M., Bengtsen, T., Larsen, A. H., Tidemand, F. G., Pedersen, M. C., Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, T., Bertarello, A., Sansom, M. S., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, K., Pintacuda, G., Arleth, L.
10.1101/2021.08.20.457080 — Posted: 2021-08-21 — Discussion: 2021-11-17  eLife
A neural hub that coordinates learned and innate courtship behaviors
Mooney, R., Ben-Tov, M., Duarte, F.
10.1101/2021.09.09.459618 — Posted: 2021-09-10 — Discussion: 2021-11-17  eLife
Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation
Singh, A. P., Wu, P., Ryabichko, S., Raimundo, J., Swan, M., Wieschaus, E., Gregor, T., Toettcher, J. E.
10.1101/2021.10.13.464280 — Posted: 2021-10-14 — Discussion: 2021-11-17  ASAPbio crowd review
Estimating salt consumption in 49 low-and middle-income countries: Development, validation and application of a machine learning model
Guzman-Vilca, W. C., Castillo-Cara, M., Carrillo-Larco, R. M.
10.1101/2021.08.31.21262944 — Posted: 2021-09-02 — Discussion: 2021-11-17  eLife
The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates
Mickolajczyk, K. J., Olinares, P. D. B., Chait, B. T., Liu, S., Kapoor, T. M.
10.1101/2021.08.30.458255 — Posted: 2021-08-31 — Discussion: 2021-11-16  eLife
Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors
Ruiz, A., Benucci, S., Duthaler, U., Bachmann, C. P., Franchini, M., Noreen, F., Pietrangelo, L., Protasi, F., Treves, S., Zorzato, F.
10.1101/2021.11.09.467894 — Posted: 2021-11-09 — Discussion: 2021-11-16  eLife
The molecular mechanism of load adaptation by branched actin networks
Li, T.-D., Bieling, P., Weichsel, J., Mullins, R. D., Fletcher, D. A.
10.1101/2021.05.24.445507 — Posted: 2021-05-25 — Discussion: 2021-11-15  eLife
{micro}-Theraphotoxin-Pn3a inhibition of Cav3.3 channels reveals a novel isoform-selective drug binding site
McArthur, J. R., Wen, J., Hung, A., Finol-Urdaneta, R. K., Adams, D. J.
10.1101/2021.10.04.463006 — Posted: 2021-10-04 — Discussion: 2021-11-15  eLife

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