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Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming.
Brickman, J. M., Perera, M., Nissen, S. B., Proks, M., Pozzi, S., Monteiro, R. S., Trusina, A.
10.1101/2022.04.03.486894 — Posted: 2022-04-05 — Discussion: 2022-08-02  eLife
Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity
Zheng, E. B., Zhao, L.
10.1101/2022.04.04.486978 — Posted: 2022-04-05 — Discussion: 2022-08-02  eLife
Evaluation of in silico predictors on short nucleotide variants in HBA1, HBA2 and HBB associated with haemoglobinopathies
Tamana, S., Xenophontos, M., Minaidou, A., Stephanou, C., Harteveld, C. L., Bento, C., Traeger-Synodinos, J., Fylaktou, I., Yasin, N. M., Hamid, F. S. A., Esa, E., Halim-Fikri, H., Zilfalil, B. A., Kakouri, A. C., ClinGen Hemoglobinopathy VCEP, , Kleanthous, M., Kountouris, P.
10.1101/2022.04.07.484934 — Posted: 2022-04-09 — Discussion: 2022-08-02  eLife
The evolution of a counter-defense mechanism in a virus constrains its host range
Srikant, S., Guegler, C. K., Laub, M. T.
10.1101/2022.04.14.488369 — Posted: 2022-04-14 — Discussion: 2022-08-02  eLife
Variable paralog expression underlies phenotype variation
Bailon-Zambrano, R., Sucharov, J., Mumme-Monheit, A., Murry, M., Stenzel, A., Pulvino, A. T., Mitchell, J., Colborn, K. L., Nichols, J.
10.1101/2022.04.27.489692 — Posted: 2022-04-28 — Discussion: 2022-08-02  eLife
An auto-inhibited state of protein kinase G and implications for selective activation
Sharma, R., Kim, J. J., Qin, L., Henning, P., Akimoto, M., VanSchouwen, B., Kaur, G., Sankaran, B., MacKenzie, K. R., Melacini, G., Casteel, D. E., Herberg, F. W., Kim, C. W.
10.1101/2022.04.28.489861 — Posted: 2022-04-28 — Discussion: 2022-08-02  eLife
Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells
Sessa, W. C., Fowler, J. W. M., Zhang, R., Tao, B., Boutagy, N. E.
10.1101/2022.05.05.490737 — Posted: 2022-05-05 — Discussion: 2022-08-02  eLife
Structure of the lysosomal membrane fusion machinery
Shvarev, D., Schoppe, J., Koenig, C., Perz, A., Fuellbrunn, N., Kiontke, S., Langemeyer, L., Januliene, D., Schnelle, K., Kuemmel, D., Froehlich, F., Moeller, A., Ungermann, C.
10.1101/2022.05.05.490745 — Posted: 2022-05-05 — Discussion: 2022-08-02  eLife
Automated systematic evaluation of cryo-EM specimens with SmartScope
Bouvette, J., Huang, Q., Riccio, A. A., Copeland, W. C., Bartesaghi, A., Borgnia, M. J.
10.1101/2022.05.05.490801 — Posted: 2022-05-06 — Discussion: 2022-08-02  eLife
Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology
Zhang, S., Zhu, Y., Lu, J., Liu, z., Lobato, A. G., Liu, J., Qiang, J., Zeng, W., Zhang, Y., Liu, C., He, Z., zhai, G., Li, D.
10.1101/2022.05.08.491088 — Posted: 2022-05-08 — Discussion: 2022-08-02  eLife

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