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Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using equilibrium competing inert hydroxymethylene diphosphonate

Okawa, H., Kondo, T., Hokugo, A., Cherian, P., Campagna, J. J., Lentini, N., Sung, S., Sung, E. C., Chiang, S. H., Lin, Y.-L., Ebetino, F. H., John, V., McKenna, C. E., Nishimura, I.

10.1101/2021.12.22.21268006 — Posted: 2021-12-29 — Discussion: 2022-08-02 eLife

Decoding mitochondrial genes in pediatric AML and development of a novel prognostic mitochondrial gene signature

Chaudhary, S., Ganguly, S., Palanichamy, J. K., Singh, A., Pradhan, D., Bakhshi, R., Chopra, A., Bakhshi, S.

10.1101/2022.04.01.22273235 — Posted: 2022-04-03 — Discussion: 2022-08-02 eLife

Associations between vitamin D and disease risk may be attributed to the confounding influence of adiposity during childhood and adulthood: a lifecourse Mendelian randomization study

Richardson, T. G., Power, G. M., Davey Smith, G.

10.1101/2022.05.11.22274956 — Posted: 2022-05-16 — Discussion: 2022-08-02 eLife

The Proportion of Randomized Controlled Trials That Inform Clinical Practice: A Longitudinal Cohort Study of Trials Registered on ClinicalTrials.gov

Hutchinson, N., Moyer, H., Zarin, D., Kimmelman, J.

10.1101/2022.05.12.22275021 — Posted: 2022-05-13 — Discussion: 2022-08-02 eLife

Early life trauma leads to violent behavior and its inheritance by impairing local thyroid hormone availability in brain

Konar, A., Rawat, R. S., Bhambri, A., Pal, M., Roy, A., Jain, S., Pillai, B.

10.1101/2021.07.05.448713 — Posted: 2021-07-05 — Discussion: 2022-08-01 eLife

Mars, a molecule archive suite for reproducible analysis and reporting of single molecule properties from bioimages

Huisjes, N. M., Retzer, T. M., Scherr, M. J., Agarwal, R., Safaric, B., Minnen, A., Duderstadt, K. E.

10.1101/2021.11.26.470105 — Posted: 2021-11-26 — Discussion: 2022-08-01 eLife

Contribution of behavioural variability to representational drift

Sadeh, S., Clopath, C.

10.1101/2022.01.02.474731 — Posted: 2022-01-02 — Discussion: 2022-08-01 eLife

Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

Gerum, R. C., Mirzahossein, E., Eroles, M., Elsterer, J., Mainka, A., Bauer, A., Sonntag, S., Winterl, A., Bartl, J., Fischer, L., Abuhattum, S., Goswami, R., Girardo, S., Guck, J., Schruefer, S., Stroehlein, N., Nosratlo, M., Herrmann, H., Schultheis, D., Rico, F., Mueller, S., Gekle, S., Fabry, B.

10.1101/2022.01.11.475843 — Posted: 2022-01-12 — Discussion: 2022-08-01 eLife

Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia

Gao, F., Li, C., Smith, S., Peinado, N., Kohbodi, G., Tran, E., Loh, E., Li, W., Borok, Z., Minoo, P.

10.1101/2022.01.24.477613 — Posted: 2022-01-25 — Discussion: 2022-08-01 eLife

Measurements of damage and repair in aging mice and humans reveals that robustness and resilience decrease with age, operate over broad timescales, and are affected differently by interventions

Farrell, S., Kane, A., Bisset, E., Howlett, S. E., Rutenberg, A. D.

10.1101/2022.03.01.482443 — Posted: 2022-03-03 — Discussion: 2022-08-01 eLife