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110 Reviews — eLife — Systems Biology

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Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance
Masson, S. W., Madsen, S., Cooke, K. C., Potter, M., Vegas, A. D., Carroll, L., Thillainadesan, S., Walder, K. R., Cooney, G. J., Morahan, G., Stöckli, J., James, D. E.
10.1101/2023.03.01.530673 — Posted: 2023-03-03 — Discussion: 2023-07-10  eLife
Genetic and dietary modulators of the inflammatory response in the gastro-intestinal tract of the BXD mouse genetic reference population
Li, X., Morel, J.-D., Benegiamo, G., Poisson, J., Bachmann, A., Rapin, A., Williams, E. G., Perino, A., Schoonjans, K., Bou Sleiman, M. S., Auwerx, J.
10.1101/2023.03.22.533818 — Posted: 2023-03-25 — Discussion: 2023-07-03  eLife
A label-free method to track individuals and lineages of budding cells
Pietsch, J. M. J., Munoz, A. F., Adjavon, D.-Y. A., Farquhar, I., Clark, I. B., Swain, P. S.
10.1101/2022.05.11.491488 — Posted: 2022-05-12 — Discussion: 2023-06-09  eLife
Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
Rodriguez, J. D., Iniguez, A., Jena, N., Tata, P., Liu, J., Lander, A. D., Lowengrub, J., Van Etten, R.
10.1101/2022.10.11.511822 — Posted: 2022-10-14 — Discussion: 2023-03-18  eLife
An unbiased pathway analysis (UPA) designed for multi-omics inference of cell signaling pathways
Vaparanta, K., Merilahti, J. A. M., Ojala, V. K., Elenius, K.
10.1101/2022.02.05.479228 — Posted: 2022-02-06 — Discussion: 2023-02-16  eLife
Resource allocation accounts for the large variabilityof rate-yield phenotypes across bacterial strains
Baldazzi, V., Ropers, D., Gouze, J.-L., Gedeon, T., de Jong, H.
10.1101/2022.04.27.489666 — Posted: 2022-04-27 — Discussion: 2023-01-25  eLife
Co-substrate pools can constrain and regulate pathway fluxes in cell metabolism
West, R., Delattre, H., Noor, E., Feliu, E., Soyer, O. S.
10.1101/2022.09.05.506656 — Posted: 2022-09-06 — Discussion: 2023-01-22  eLife
Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy
Sayin, S., Rosener, B., Li, C. G., Ho, B., Ponomarova, O., Ward, D., Walhout, A. J., Mitchell, A.
10.1101/2022.09.07.506952 — Posted: 2022-09-07 — Discussion: 2022-12-19  eLife
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function
Molendijk, J., Blazev, R., Mills, R., Ng, Y.-K., Watt, K. I., Chau, D., Gregorevic, P., Crouch, P. J., Hilton, J. B., Lisowski, L., Zhang, P., Reue, K., Lusis, A. J., Hudson, J. E., James, D. E., Seldin, M. M., Parker, B. L.
10.1101/2022.08.22.504871 — Posted: 2022-08-22 — Discussion: 2022-11-22  eLife
A unified framework for measuring selection on cellular lineages and traits
Yamauchi, S., Nozoe, T., Okura, R., Kussell, E., Wakamoto, Y.
10.1101/2021.07.18.452747 — Posted: 2021-07-19 — Discussion: 2022-10-19  eLife

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