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IL-21 lowers the B cell receptor affinity threshold for participation in a T cell dependent immune response.
Dvorscek, A. R., McKenzie, C. I., Robinson, M. J., Ding, Z., Pitt, C., O'Donnell, K., Zotos, D., Brink, R., Tarlinton, D. M., Quast, I.
10.1101/2022.01.21.476732 — Posted: 2022-01-22 — Discussion: 2022-11-21  EMBO Press
Dynamic human liver proteome atlas reveals functional insights into disease pathways
Mann, M., Niu, L., Geyer, P., Gupta, R., Santos, A., Meier, F., Doll, S., Wewer Albrechtsen, N. J., Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J.
10.1101/2022.01.28.478194 — Posted: 2022-01-31 — Discussion: 2022-11-21  EMBO Press
Changes in chromatin accessibility are not concordant with transcriptional changes for single-factor perturbations
Kiani, K., Sanford, E. M., Goyal, Y., Raj, A.
10.1101/2022.02.03.478981 — Posted: 2022-02-03 — Discussion: 2022-11-21  EMBO Press
Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
Mukhtar, T., Breda, J., Boareto, M., Grobecker, P., Karimaddini, Z., Grison, A., Eschbach, K., Chandrasekhar, R., Vermeul, S., Okoniewski, M., Pachkov, M., Atanasoski, S., Beisel, C., Iber, D., Nimwegen, E. v., Taylor, V.
10.1101/2022.02.10.479992 — Posted: 2022-02-11 — Discussion: 2022-11-21  EMBO Press
Lifespan can be extended during a specific time window early in life
Tiberi, L.
10.1101/2022.02.18.480980 — Posted: 2022-02-19 — Discussion: 2022-11-21  EMBO Press
Quantifying the phenotypic information in mRNA abundance
Maltz, E. W., Wollman, R.
10.1101/2022.02.23.481668 — Posted: 2022-02-24 — Discussion: 2022-11-21  EMBO Press
ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain of function
Pant, D., Parameswaran, J., Rao, L., Shi, L., Chilukuri, G., McEachin, Z., Glass, J., Bassell, G. J., Gennerich, A., Jiang, J.
10.1101/2022.03.05.483071 — Posted: 2022-03-07 — Discussion: 2022-11-21  EMBO Press
Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.
Vertesy, A., Eichmueller, O. L., Naas, J., Novatchkova, M., Esk, C., Balmana, M., Ladstaetter, S., Bock, C., von Haeseler, A., Knoblich, J. A.
10.1101/2022.03.11.483643 — Posted: 2022-03-12 — Discussion: 2022-11-21  EMBO Press
Structure and functional mapping of the KRAB-KAP1 repressor complex
Stoll, G. A., Pandiloski, N., Douse, C. H., Modis, Y.
10.1101/2022.03.17.484746 — Posted: 2022-03-17 — Discussion: 2022-11-21  EMBO Press
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium
Johnson, N. M., Parham, L. R., Na, J., Monaghan, K. E., Kolev, H. M., Klochkova, A., Kim, M. S., Danan, C. H., Cramer, Z., Simon, L. A., Naughton, K. E., Adams-Tzivelekidis, S., Tian, Y., Williams, P. A., Leu, N. A., Sidoli, S., Whelan, K. A., Li, N., Lengner, C. J., Hamilton, K. E.
10.1101/2022.04.08.487404 — Posted: 2022-04-10 — Discussion: 2022-11-21  EMBO Press

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