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Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
Van Ravenstein, S. X., Mehta, K. P., Kavlashvili, T., Byl, J. A., Zhao, R., Osheroff, N., Cortez, D., Dewar, J. M.
10.1101/2021.10.12.464107 — Posted: 2021-10-12 — Discussion: 2022-11-21  EMBO Press
HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
Kim, J., Park, J., Kim, H., Son, N., Lambing, C., Kim, E.-J., Kim, J., Byun, D., Lee, Y., Park, Y. M., Nageswaran, D. C., Kuo, P., Dang, T. V. T., Hwang, I., Henderson, I. R., Choi, K.
10.1101/2021.10.17.464477 — Posted: 2021-10-18 — Discussion: 2022-11-21  EMBO Press
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67
van Schaik, T., Manzo, S. G., Vouzas, A. E., Gilbert, D. M., van Steensel, B.
10.1101/2021.10.20.465140 — Posted: 2021-10-20 — Discussion: 2022-11-21  EMBO Press
Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity
Neumann, C. M. T., Rosenbaek, L. L., Flygaard, R. K., Habeck, M., Karlsen, J. L., Wang, Y., Lindorff-Larsen, K., Gad, H. H., Hartmann, R., Lyons, J., Fenton, R. A., Nissen, P.
10.1101/2021.11.11.468215 — Posted: 2021-11-12 — Discussion: 2022-11-21  EMBO Press
Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages
Dao, T. P., Yang, Y., Cosgrove, M. S., Hopkins, J. B., Ma, W., Castaneda, C. A.
10.1101/2021.11.12.467822 — Posted: 2021-11-13 — Discussion: 2022-11-21  EMBO Press
TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
Tufan, A. B., Lazarow, K., Kolesnichenko, M., Sporbert, A., von Kries, J. P., Scheidereit, C.
10.1101/2021.12.07.471537 — Posted: 2021-12-09 — Discussion: 2022-11-21  EMBO Press
Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions
Yifrach, E., Holbrook-Smith, D., Bürgi, J., Othman, A., Eisenstein, M., Van Roermund, C. W. T., Visser, W., Tirosh, A., Bibi, C., Galor, S., Weil, U., Fadel, A., Peleg, Y., Waterham, H., Wanders, R. J., Wilmanns, M., Zamboni, N., Schuldiner, M., Zalckvar, E.
10.1101/2021.12.08.471723 — Posted: 2021-12-11 — Discussion: 2022-11-21  EMBO Press
Regulation of mitochondrial proteostasis by the proton gradient
Patron, M., Tarasenko, D., Nolte, H., Ghosh, M., Ohba, Y., Lasarzewksi, Y., Ahmadi, Z. A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E. I., Brandt, U., Meinecke, M., Langer, T.
10.1101/2021.12.12.470907 — Posted: 2021-12-12 — Discussion: 2022-11-21  EMBO Press
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Gorbunova, V., Simon, M., Trombline, G., Yang, J., Earley, E. J., Zhang, L., Gigas, J., Zagorulya, M., Gilbert, M., Robbins, P. D., Vijg, J., Seluanov, A., Suh, Y., Garcia, B., Thomas, D. D., Yuen, S. L., Pope, A., Van Meter, M., Emmrich, S., Moody, K., Barzilai, N., Wolfe, A., Atzmon, G., Schaff, T. M.
10.1101/2021.12.13.472381 — Posted: 2021-12-13 — Discussion: 2022-11-21  EMBO Press
Endothelial-immune crosstalk contributes to vasculopathy in non-alcoholic fatty liver disease
Ng, C.-Y., Lee, K. L., Muthiah, M. D., Wu, K. X., Chioh, F., Tan, K., Soon, G., Shabbir, A., Loo, W. M., Low, Z. S., Chen, Q., Tan, N. S., Ng, H.-H., Dan, Y. Y., Cheung, C.
10.1101/2021.12.13.472411 — Posted: 2021-12-14 — Discussion: 2022-11-21  EMBO Press

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