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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Gorbunova, V., Simon, M., Trombline, G., Yang, J., Earley, E. J., Zhang, L., Gigas, J., Zagorulya, M., Gilbert, M., Robbins, P. D., Vijg, J., Seluanov, A., Suh, Y., Garcia, B., Thomas, D. D., Yuen, S. L., Pope, A., Van Meter, M., Emmrich, S., Moody, K., Barzilai, N., Wolfe, A., Atzmon, G., Schaff, T. M.
10.1101/2021.12.13.472381 — Posted: 2021-12-13 — Discussion: 2022-11-21  EMBO Press
Endothelial-immune crosstalk contributes to vasculopathy in non-alcoholic fatty liver disease
Ng, C.-Y., Lee, K. L., Muthiah, M. D., Wu, K. X., Chioh, F., Tan, K., Soon, G., Shabbir, A., Loo, W. M., Low, Z. S., Chen, Q., Tan, N. S., Ng, H.-H., Dan, Y. Y., Cheung, C.
10.1101/2021.12.13.472411 — Posted: 2021-12-14 — Discussion: 2022-11-21  EMBO Press
Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
Faucon, A., Samaroo, J., Ge, T., Davis, L. K., Tao, R., Cox, N. J., Shuey, M. M.
10.1101/2021.12.27.474263 — Posted: 2021-12-27 — Discussion: 2022-11-21  EMBO Press
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
Meister, M. T., Groot Koerkamp, M. J. A., de Souza, T., Breunis, W. B., Frazer-Mendelewska, E., Brok, M., DeMartino, J., Manders, F., Calandrini, C., Kerstens, H. H. D., Janse, A., Dolman, M. E. M., Eising, S., Langenberg, K. P. S., van Tuil, M., Knops, R. R. G., Terwisscha van Scheltinga, S., Hiemcke-Jiwa, L. S., Flucke, U., Merks, J. H. M., van Noesel, M. M., Tops, B. B. J., Hehir-Kwa, J. Y., Kemmeren, P., Molenaar, J. J., van de Wetering, M., van Boxtel, R., Drost, J., Holstege, F. C. P.
10.1101/2022.01.03.474504 — Posted: 2022-01-04 — Discussion: 2022-11-21  EMBO Press
RNA-mediated nucleosome depletion is required for elimination of transposon-derived DNA.
Singh, A., Maurer-Alcala, X. X., Solberg, T., Gisler, S., Ignarski, M., Swart, E. C., Nowacki, M.
10.1101/2022.01.04.474918 — Posted: 2022-01-05 — Discussion: 2022-11-21  EMBO Press
Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models
Sauer, C. M., Heider, K., Belic, J., Boyle, S. E., Hall, J. A., Couturier, D.-L., An, A., Vijayaraghavan, A., Reinius, M. A., Hosking, K., Vias, M., Rosenfeld, N., Brenton, J. D.
10.1101/2022.01.15.476442 — Posted: 2022-01-18 — Discussion: 2022-11-21  EMBO Press
IL-21 lowers the B cell receptor affinity threshold for participation in a T cell dependent immune response.
Dvorscek, A. R., McKenzie, C. I., Robinson, M. J., Ding, Z., Pitt, C., O'Donnell, K., Zotos, D., Brink, R., Tarlinton, D. M., Quast, I.
10.1101/2022.01.21.476732 — Posted: 2022-01-22 — Discussion: 2022-11-21  EMBO Press
Dynamic human liver proteome atlas reveals functional insights into disease pathways
Mann, M., Niu, L., Geyer, P., Gupta, R., Santos, A., Meier, F., Doll, S., Wewer Albrechtsen, N. J., Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J.
10.1101/2022.01.28.478194 — Posted: 2022-01-31 — Discussion: 2022-11-21  EMBO Press
Changes in chromatin accessibility are not concordant with transcriptional changes for single-factor perturbations
Kiani, K., Sanford, E. M., Goyal, Y., Raj, A.
10.1101/2022.02.03.478981 — Posted: 2022-02-03 — Discussion: 2022-11-21  EMBO Press
Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
Mukhtar, T., Breda, J., Boareto, M., Grobecker, P., Karimaddini, Z., Grison, A., Eschbach, K., Chandrasekhar, R., Vermeul, S., Okoniewski, M., Pachkov, M., Atanasoski, S., Beisel, C., Iber, D., Nimwegen, E. v., Taylor, V.
10.1101/2022.02.10.479992 — Posted: 2022-02-11 — Discussion: 2022-11-21  EMBO Press

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