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A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
Tian, Q., Zhang, P., Wang, Y., Si, Y., Yin, D., Weber, C. R., Fishel, M., Pollok, K. E., Qiu, B., Xiao, F., Chong, A.
10.1101/2023.02.15.528599 — Posted: 2023-02-15 — Discussion: 2023-09-28  eLife
Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease
Ramirez Flores, R. O., Lanzer, J. D., Dimitrov, D., Velten, B., Saez-Rodriguez, J.
10.1101/2023.02.23.529642 — Posted: 2023-02-23 — Discussion: 2023-09-28  Review Commons
New insights into the role of the microbiota in Ornithodoros moubata: Influence of endosymbionts on the reproductive fitness of the tick
Taraveau, F., Pollet, T., Duhayon, M., Gardes, L., Jourdan-Pineau, H.
10.1101/2023.05.09.539061 — Posted: 2023-05-10 — Discussion: 2023-09-28  Peer Community In
Homeostasis, injury and recovery dynamics at multiple scales in a self-organizing intestinal crypt
Gall, L., Duckworth, C., Jardi, F., Lammens, L., Parker, A., Bianco, A., Kimko, H., Pritchard, D. M., Pin, C.
10.1101/2022.12.18.520934 — Posted: 2022-12-19 — Discussion: 2023-09-27  eLife
Single-cell Sequencing Highlights Heterogeneity and Malignant Progression in Actinic Keratosis and Cutaneous Squamous Cell Carcinoma
Zou, D.-D., Sun, Y.-Z., Li, X.-J., Wu, W.-J., Xu, D., He, Y.-T., Qi, J., Tu, Y., Tang, Y., Tu, Y.-H., Wang, X.-L., Li, X., Lu, F.-Y., Huang, L., Long, H., He, L., Li, X.
10.1101/2022.12.22.521622 — Posted: 2022-12-22 — Discussion: 2023-09-27  eLife
Death by a Thousand Cuts -- Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology
Outhwaite, I. R., Singh, S., Berger, B.-T., Knapp, S., Chodera, J. D., Seeliger, M. A.
10.1101/2023.01.13.523972 — Posted: 2023-01-16 — Discussion: 2023-09-27  eLife
Identification of a carbohydrate-recognition motif of purinergic receptors
Zhao, L., Wei, F., He, X., Jiang, H., Wen, L., Cheng, X.
10.1101/2023.03.06.531346 — Posted: 2023-03-06 — Discussion: 2023-09-27  eLife
Microbially-derived indole-3-acetate alleviates diet induced steatosis and inflammation in mice
Ding, Y., Yanagi, K., Yang, F., Callaway, E., Cheng, C., Hensel, M., Menon, R., Alaniz, R., Lee, K., Jayaraman, A.
10.1101/2023.03.21.533660 — Posted: 2023-03-23 — Discussion: 2023-09-27  eLife
Genetic and karyotype divergence between parents affect clonality and sterility in hybrids
Marta, A., Tichopad, T., Bartos, O., Klima, J., shah, M., Bohlen, V. S., Bohlen, J., Halacka, K., Choleva, L., Stöck, M., Dedukh, D., Janko, K.
10.1101/2023.04.11.536494 — Posted: 2023-04-14 — Discussion: 2023-09-27  eLife
Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients
Hariharan, S., Lorintiu, O., Lee, C. W., Duchemin-Pelletier, E., Li, X., Healy, A., Doyonnas, R., Selig, L., Poydenot, P., Ventre, E., Weston, A., Owens, J., Christoforou, N.
10.1101/2023.05.24.542079 — Posted: 2023-05-24 — Discussion: 2023-09-27  eLife

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