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Death by a Thousand Cuts -- Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology
Outhwaite, I. R., Singh, S., Berger, B.-T., Knapp, S., Chodera, J. D., Seeliger, M. A.
10.1101/2023.01.13.523972 — Posted: 2023-01-16 — Discussion: 2023-09-27  eLife
Identification of a carbohydrate-recognition motif of purinergic receptors
Zhao, L., Wei, F., He, X., Jiang, H., Wen, L., Cheng, X.
10.1101/2023.03.06.531346 — Posted: 2023-03-06 — Discussion: 2023-09-27  eLife
Microbially-derived indole-3-acetate alleviates diet induced steatosis and inflammation in mice
Ding, Y., Yanagi, K., Yang, F., Callaway, E., Cheng, C., Hensel, M., Menon, R., Alaniz, R., Lee, K., Jayaraman, A.
10.1101/2023.03.21.533660 — Posted: 2023-03-23 — Discussion: 2023-09-27  eLife
Genetic and karyotype divergence between parents affect clonality and sterility in hybrids
Marta, A., Tichopad, T., Bartos, O., Klima, J., shah, M., Bohlen, V. S., Bohlen, J., Halacka, K., Choleva, L., Stöck, M., Dedukh, D., Janko, K.
10.1101/2023.04.11.536494 — Posted: 2023-04-14 — Discussion: 2023-09-27  eLife
Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients
Hariharan, S., Lorintiu, O., Lee, C. W., Duchemin-Pelletier, E., Li, X., Healy, A., Doyonnas, R., Selig, L., Poydenot, P., Ventre, E., Weston, A., Owens, J., Christoforou, N.
10.1101/2023.05.24.542079 — Posted: 2023-05-24 — Discussion: 2023-09-27  eLife
Drosophila axis extension is robust to an orthogonal pull by invaginating mesoderm
Lye, C. M., Blanchard, G. B., Evans, J., Nestor-Bergmann, A., Sanson, B.
10.1101/2023.07.18.549479 — Posted: 2023-07-19 — Discussion: 2023-09-27  Review Commons
An evolutionarily conserved mechanism for control the translation of long proteins
Zheng, X., Chen, H., Deng, Z., Wu, Y., Wu, C., Zhong, L., Yan, S.
10.1101/2022.02.13.480182 — Posted: 2022-02-14 — Discussion: 2023-09-26  Review Commons
Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Kandola, T., Venkatesan, S., Zhang, J., Lerbakken, B. T., Von Schulze, A., Blanck, J. F., Wu, J., Unruh, J. R., Berry, P., Lange, J. J., Box, A. C., Cook, M., Sagui, C., Halfmann, R.
10.1101/2023.03.20.533418 — Posted: 2023-03-21 — Discussion: 2023-09-26  eLife
Novel expression of major histocompatibility complex II in dorsal root ganglion neurons attenuates paclitaxel-induced cold hypersensitivity in male and female mice
Whitaker, E. E., Mecum, N. E., Cott, R. C., Goode, D. J.
10.1101/2023.03.31.535136 — Posted: 2023-04-03 — Discussion: 2023-09-26  Review Commons
Astrocytes gate long-term potentiation in hippocampal interneurons
Shen, W., Tang, Y., Yang, J., Zhu, L., Zhou, W., Xiang, L., Zhu, F., Dong, J., Xie, Y., Zeng, L.-H.
10.1101/2023.06.20.545820 — Posted: 2023-06-24 — Discussion: 2023-09-26  eLife

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