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1,205 Reviews — EMBO Press — All Subjects

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Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
Van Ravenstein, S. X., Mehta, K. P., Kavlashvili, T., Byl, J. A., Zhao, R., Osheroff, N., Cortez, D., Dewar, J. M.
10.1101/2021.10.12.464107 — Posted: 2021-10-12 — Discussion: 2022-11-21  EMBO Press
Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions
Yifrach, E., Holbrook-Smith, D., Bürgi, J., Othman, A., Eisenstein, M., Van Roermund, C. W. T., Visser, W., Tirosh, A., Bibi, C., Galor, S., Weil, U., Fadel, A., Peleg, Y., Waterham, H., Wanders, R. J., Wilmanns, M., Zamboni, N., Schuldiner, M., Zalckvar, E.
10.1101/2021.12.08.471723 — Posted: 2021-12-11 — Discussion: 2022-11-21  EMBO Press
Naked mole-rat hematopoietic stem and progenitors are highly quiescent with an inherent myeloid bias
Emmrich, S., Trapp, A., Tolibzoda Zakusilo, F., Mariotti, M., Straight, M. E., Zhang, Z., Gray, S., Drage, M. G., Ke, Z., Takasugi, M., Klusmann, J.-H., Gladyshev, V. N., Seluanov, A., Gorbunova, V.
10.1101/2021.08.01.454652 — Posted: 2021-08-01 — Discussion: 2022-11-21  EMBO Press
Structure and functional mapping of the KRAB-KAP1 repressor complex
Stoll, G. A., Pandiloski, N., Douse, C. H., Modis, Y.
10.1101/2022.03.17.484746 — Posted: 2022-03-17 — Discussion: 2022-11-21  EMBO Press
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
Meister, M. T., Groot Koerkamp, M. J. A., de Souza, T., Breunis, W. B., Frazer-Mendelewska, E., Brok, M., DeMartino, J., Manders, F., Calandrini, C., Kerstens, H. H. D., Janse, A., Dolman, M. E. M., Eising, S., Langenberg, K. P. S., van Tuil, M., Knops, R. R. G., Terwisscha van Scheltinga, S., Hiemcke-Jiwa, L. S., Flucke, U., Merks, J. H. M., van Noesel, M. M., Tops, B. B. J., Hehir-Kwa, J. Y., Kemmeren, P., Molenaar, J. J., van de Wetering, M., van Boxtel, R., Drost, J., Holstege, F. C. P.
10.1101/2022.01.03.474504 — Posted: 2022-01-04 — Discussion: 2022-11-21  EMBO Press
Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation
Zhu, K., Wang, Y., Sarlus, H., Geng, K., Nutma, E., Sun, J., Kang, S.-Y., Bay, C., Han, J., Lund, H., Amor, S., Wang, J., Zhang, X.-m., Kutter, C., Ortlieb, A., Hogberg, B., Harris, R.
10.1101/2021.10.04.462880 — Posted: 2021-10-04 — Discussion: 2022-11-21  EMBO Press
Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
Gomar-Alba, M., Pozharskaia, V., Schaal, C., Kumar, A., Jacquel, B., Charvin, G., Igual, J. C., Mendoza, M.
10.1101/2021.09.01.458533 — Posted: 2021-09-01 — Discussion: 2022-11-21  EMBO Press
Parkin coordinates mitochondrial lipid remodeling to execute mitophagy
Lin, C.-C., Yan, J., Kapur, M. D., Norris, K. L., Hsieh, C.-W., Lai, C.-H., Vitale, N., Lim, K.-L., Guan, Z., Chi, J.-T., Yang, W.-Y., Yao, T.-P.
10.1101/2020.02.28.970210 — Posted: 2020-02-28 — Discussion: 2022-11-21  EMBO Press
Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages
Dao, T. P., Yang, Y., Cosgrove, M. S., Hopkins, J. B., Ma, W., Castaneda, C. A.
10.1101/2021.11.12.467822 — Posted: 2021-11-13 — Discussion: 2022-11-21  EMBO Press
Optogenetic actuator/biosensor circuits for large-scale interrogation of ERK dynamics identify sources of MAPK signaling robustness.
Dessauges, C., Mikelson, J., Dobrzynski, M., Jacques, M.-A., Frismantiene, A., Gagliardi, P. A., Khammash, M., Pertz, O.
10.1101/2021.07.27.453955 — Posted: 2021-07-27 — Discussion: 2022-11-21  EMBO Press

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