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101 Reviews — EMBO Press — Systems Biology

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Genome-scale metabolic modeling reveals SARS-CoV-2-induced host metabolic reprogramming and identifies metabolic antiviral targets
Cheng, K., Riva, L., Sinha, S., Pal, L. R., Nair, N. U., Martin-Sancho, L., Chanda, S. K., Ruppin, E.
10.1101/2021.01.27.428543 — Posted: 2021-01-28 — Discussion: 2021-12-01  EMBO Press
Exploring amino acid functions in a deep mutational landscape
Dunham, A., Beltrao, P.
10.1101/2020.05.26.116756 — Posted: 2020-05-27 — Discussion: 2021-10-30  EMBO Press
Evaluating the Simple Arrhenius Equation for the Temperature Dependence of Complex Developmental Processes
Crapse, J., Pappireddi, N., Gupta, M., Shvartsman, S. Y., Wieschaus, E., Wuhr, M.
10.1101/2020.07.17.208777 — Posted: 2020-07-18 — Discussion: 2021-09-30  EMBO Press
Identification of Covalent Modifications Regulating Immune Signaling Complex Composition and Phenotype
Frauenstein, A., Ebner, S., Sinha, A., Kshiti, P., Swatek, K., Hornburg, D., Mann, M., Meissner, F.
10.1101/2020.11.16.384750 — Posted: 2020-11-17 — Discussion: 2021-08-13  EMBO Press
TNF stimulation primarily modulates transcriptional burst size of NF-κB-regulated genes
Bass, V. L., Wong, V. C., Bullock, M. E., Gaudet, S., Miller-Jensen, K.
10.1101/2020.11.16.384297 — Posted: 2020-11-17 — Discussion: 2021-08-13  EMBO Press
Single-cell transcriptomics reveals immune response of intestinal cell types to viral infection
Triana, S., Stanifer, M. L., Shahraz, M., Mukenhirn, M., Kee, C., Ordonez Rueda, D., Paulsen, M., Benes, V., Boulant, S., Alexandrov, T.
10.1101/2020.08.19.255893 — Posted: 2020-08-19 — Discussion: 2021-08-13  EMBO Press
Tunable phenotypic variability through an autoregulatory alternative sigma factor circuit
Schwall, C. P., Loman, T., Martins, B. M. C., Cortijo, S., Villava, C., Kusmartsev, V., Livesey, T., Saez, T., Locke, J. C. W.
10.1101/2020.06.18.158790 — Posted: 2020-06-18 — Discussion: 2021-08-13  EMBO Press
Behavioral fingerprints predict insecticide and anthelmintic mode of action
McDermott-Rouse, A., Minga, E., Barlow, I., Feriani, L., Harlow, P. H., Flemming, A. J., Brown, A.
10.1101/2021.01.27.428391 — Posted: 2021-01-28 — Discussion: 2021-07-17  EMBO Press
JSTA: joint cell segmentation and cell type annotation for spatial transcriptomics
Littman, R., Hemminger, Z., Foreman, R., Arneson, D., Zhang, G., Gomez-Pinilla, F., Yang, X., Wollman, R.
10.1101/2020.09.18.304147 — Posted: 2020-09-20 — Discussion: 2021-07-17  EMBO Press
hu.MAP 2.0: Integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies
Drew, K., Wallingford, J. B., Marcotte, E. M.
10.1101/2020.09.15.298216 — Posted: 2020-09-16 — Discussion: 2021-05-19  EMBO Press

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