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7,957 Reviews — eLife — All Subjects

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Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration
DEY, D., Marciano, S., Poryvai, A., Groborz, O., wohlrabova, L., Slanina, T., Schreiber, G.
10.1101/2023.04.19.537456 — Posted: 2023-04-21 — Discussion: 2024-11-14  eLife
Conformational dynamics of a nicotinic receptor neurotransmitter binding site
Singh, M., Indurthi, D. C., Mittal, L., Auerbach, A., Asthana, S.
10.1101/2023.09.16.558050 — Posted: 2023-09-17 — Discussion: 2024-11-14  eLife
TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma
Tian, M., Yang, L., Zhao, Z., Li, J., Wang, L., Yin, Q., Hu, W., Lou, Y., Du, J., Zhao, P.
10.1101/2023.11.14.567124 — Posted: 2023-11-16 — Discussion: 2024-11-14  eLife
Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Joseph, R. E., Wales, T. E., Jayne, S., Britton, R. G., Fulton, D. B., Engen, J. R., Dyer, M. J. S., Andreotti, A.
10.1101/2023.12.18.572223 — Posted: 2023-12-18 — Discussion: 2024-11-14  eLife
Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development
Poltavski, D. M., Cunha, A. T., Tan, J. V. S., Sucov, H. M., Makita, T.
10.1101/2024.02.13.580135 — Posted: 2024-02-14 — Discussion: 2024-11-14  eLife
Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8
Rai, A., Janning, P., Vetter, I. R., Goody, R. S.
10.1101/2024.06.17.599268 — Posted: 2024-06-17 — Discussion: 2024-11-14  eLife
Basal Cambrian soft-bodied segmented bilaterians preserved as microbial pseudomorphs
Yang, X., Wang, D., Zhang, Z., Wang, X., Sun, J., Hao, W., Liu, Y., Uesugi, K., Komiya, T., Han, J.
10.1101/2024.07.03.601876 — Posted: 2024-07-05 — Discussion: 2024-11-14  eLife
Structure of human PIEZO1 and its slow inactivating channelopathy mutants
Shan, Y., Guo, X., Zhang, M., Chen, M., Li, Y., Zhang, M., Pei, D.
10.1101/2024.07.14.603468 — Posted: 2024-07-16 — Discussion: 2024-11-14  eLife
Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785
Zhang, S., Stix, R., Orabi, E. A., Bernhardt, N., Faraldo-Gomez, J. D.
10.1101/2024.07.25.605170 — Posted: 2024-07-25 — Discussion: 2024-11-14  eLife
Osterix Facilitates Osteocytic Communication by Targeting Connexin43
wu, z., chen, q., gao, q., Liang, m., Zhou, y., Zhu, L., wang, j., Shen, Y., Jing, j., Xie, J., Liu, X., zou, S., Zhang, D., Zhou, C.
10.1101/2024.09.09.611984 — Posted: 2024-09-09 — Discussion: 2024-11-14  eLife

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