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Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation
Miao, Y., Du, Y., Wang, B., Liang, J., Liang, Y., Dang, S., Liu, J., Li, D., He, K., Ding, M.
10.1101/2024.01.10.575034 — Posted: 2024-01-11 — Discussion: 2024-10-18  eLife
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma
Shang, J., Kojetin, D.
10.1101/2024.05.15.594037 — Posted: 2024-05-15 — Discussion: 2024-10-18  eLife
Direct and Indirect Salt Effects on Homotypic Phase Separation
MacAinsh, M., Dey, S., Zhou, H.-X.
10.1101/2024.05.26.596000 — Posted: 2024-05-31 — Discussion: 2024-10-18  eLife
Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
Hong, Z., Wang, K., Zada, Z., Gazula, H., Turner, D., Aubrey, B., Niekerken, L., Doyle, W., Devore, S., Dugan, P., Friedman, D., Devinsky, O., Flinker, A., Hasson, U., Nastase, S., Goldstein, A.
10.1101/2024.06.12.598513 — Posted: 2024-06-13 — Discussion: 2024-10-18  eLife
The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain
Saeb, D., Lietzke, E. E., Fuchs, D. I., Aldrich, E. C., Bruce, K. D., Sprenger, K. G.
10.1101/2024.09.04.611223 — Posted: 2024-09-07 — Discussion: 2024-10-18  eLife
Prolonged DNA Damage Checkpoint Arrest Requires Constant Renewal and the Spindle Assembly Checkpoint
Zhou, F. Y., Waterman, D. P., Caban-Penix, S., Eapen, V. V., Haber, J. E.
10.1101/2023.05.15.540538 — Posted: 2023-05-15 — Discussion: 2024-10-17  eLife
Inhibition of Notch activity by phosphorylation of CSL in response to parasitization in Drosophila
Deichsel, S., Frankenreiter, L., Fechner, J., Gahr, B. M., Zimmermann, M., Mastel, H., Preis, I., Preiss, A., Nagel, A. C.
10.1101/2023.06.16.545247 — Posted: 2023-06-17 — Discussion: 2024-10-17  eLife
Diversity in Notch ligand-receptor signaling interactions
Kuintzle, R., Santat, L. A., Elowitz, M. B.
10.1101/2023.08.24.554677 — Posted: 2023-08-25 — Discussion: 2024-10-17  eLife
PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, P. falciparum.
Chahine, Z. M., Gupta, M., Lenz, T., Hollin, T., Abel, S., Banks, C., Saraf, A., Prudhomme, J., Florens, L., Le Roch, K. G.
10.1101/2023.09.11.557253 — Posted: 2023-09-11 — Discussion: 2024-10-17  eLife
Heparan sulphate binding controls in vivo half-life of the HpARI protein family
Colomb, F., Jamwal, A., Ogunkanbi, A., Frangova, T., Savage, A. R., Kelly, S., Wright, G. J., Higgins, M. K., McSorley, H. J.
10.1101/2024.05.06.592731 — Posted: 2024-05-11 — Discussion: 2024-10-17  eLife

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