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Systematic overexpression reveals a conserved spectrum of harmful and beneficial amino acid homorepeats shaped by evolution
Murase, Y., Kitamura, N., Namba, S., Satoh, A., Makino, T., Moriya, A., Moriya, H.
10.64898/2025.12.19.695406 — Posted: 2025-12-22 — Discussion: 2026-03-11  eLife
Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules
Karanicolas, J.
10.64898/2026.01.02.697373 — Posted: 2026-01-02 — Discussion: 2026-03-11  eLife
Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans
Xu, Z., Feng, X., Lyu, H., Yan, Y.-H., Zhou, Y., Wang, Z., Bai, F., Dong, M.-Q., Qi, Y. B.
10.64898/2026.01.08.698494 — Posted: 2026-01-09 — Discussion: 2026-03-11  eLife
ARID5B mutations cause a neurodevelopmental syndrome with neuroinflammation episodes
van Heesbeen, H., Rabouhi, N., Gouronc, A., Preto, A., Rousseau, J., Charbonneau, J., Vitobello, A., Bruel, A.-L., Denomme-Pichon, A.-S., Colin, E., Isidor, B., Nambot, S., DeMille, D., Bayrak-Toydemir, P., Longo, N., Keren, B., Afenjar, A., Klein Wassink-Ruiter, J. S., Krapels, I. P. C., Titheradge, H., Ryan, G., Wagner, M., Rosenfeld, J. A., Witt, D. R., Saronwala, A., Yang, Y., ROTHSCHILD, A., Barel, O., Jethva, R., Wortmann, S. B., Diepold, K., Rostasy, K., Clarkson, L. K., Drazba, K. T., Louie, R., Goel, H., Kuismin, O., Nokelainen, P., Ji, J., Mills, A., Deardorff, M. A., Palomares-Bralo
10.64898/2026.01.15.698931 — Posted: 2026-01-19 — Discussion: 2026-03-11  eLife
Circadian photoreceptor CRYPTOCHROME promotes wakefulness under short winter-like days via a GABAergic circuitry
Chen, L., Tian, D., Su, C., Zhang, L.
10.1101/2023.10.02.560507 — Posted: 2023-10-02 — Discussion: 2026-03-10  eLife
Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum
Lenz, T., Sirel, M., Hoppe, H., Shafeeq, S., Le Roch, K., Ribacke, U.
10.1101/2023.11.14.567110 — Posted: 2023-11-15 — Discussion: 2026-03-10  eLife
Individuality across environmental context in Drosophila melanogaster
Mathejczyk, T., Knief, C., Haidar, M. A., Freitag, F., McClary, T., Wernet, M. F., Linneweber, G. A.
10.1101/2023.11.26.568741 — Posted: 2023-11-26 — Discussion: 2026-03-10  eLife
Coma pattern-based autofocusing unlocks superior performance in unravelling single-cell dynamics during bacterial cold shock response
Li, S., Ma, Z., Yu, Y., Wang, J., Shen, Y., Cui, X., Fu, X., Huang, S.
10.1101/2024.10.15.618375 — Posted: 2024-10-16 — Discussion: 2026-03-10  eLife
The population structure of invasive Lantana camara is shaped by its mating system
Praveen, P., Gopal, R., Ramakrishnan, U.
10.1101/2024.10.22.619585 — Posted: 2024-10-25 — Discussion: 2026-03-10  eLife
Thymic selection of the T cell receptor repertoire is biased toward autoimmunity in females
Vantomme, H., Quiniou, V., Adda, L., Jouannet, C., Mhanna, V., Albalaa, C., Barennes, P., Coatnoan, N., Diderot, V., Dubois, J., Fourcade, G., Le Gouge, K., Nguekap Tchoumba, O., Pezous, M., Stys, P., Six, A., Mariotti Ferrandiz, E., Klatzmann, D.
10.1101/2025.01.21.633929 — Posted: 2025-01-23 — Discussion: 2026-03-10  eLife

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