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The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy
Hama, Y., Fujioka, Y., Yamamoto, H., Mizushima, N., Noda, N. N.
10.1101/2024.08.02.606296 — Posted: 2024-08-02 — Discussion: 2025-06-05  eLife
Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments
Flowers, J., Echols, N., Correy, G., Jaishankar, P., Togo, T., Renslo, A. R., van den Bedem, H., Fraser, J. S., Wankowicz, S. A.
10.1101/2024.09.20.613996 — Posted: 2024-09-23 — Discussion: 2025-06-05  eLife
A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins.
Kelpsch, D. J., Zhang, L., Thierer, J. H., Koren, K., Kumar, U., Lin, Y., Hensley, M. R., Sohn, M., Liu, J. O., Lectka, T., Mumm, J. S., Farber, S. A.
10.1101/2024.11.14.623618 — Posted: 2024-11-15 — Discussion: 2025-06-05  eLife
Old age variably impacts chimpanzee engagement and efficiency in stone tool use
Howard-Spink, E., Matsuzawa, T., Carvalho, S., Hobaiter, C., Almeida-Warren, K., Gruber, T., Biro, D.
10.1101/2024.11.25.625128 — Posted: 2024-11-25 — Discussion: 2025-06-05  eLife
A Commander-independent function of COMMD3 in endosomal trafficking
Squiers, G. T., Wan, C., Gorder, J., Puscher, H., Shen, J.
10.1101/2024.12.12.628173 — Posted: 2024-12-17 — Discussion: 2025-06-05  eLife
Reversible One-way Lipid Transfer at ER-Autophagosome Membrane Contact Sites via Bridge-like Lipid Transfer Protein Atg2
Hao, L., Midorikawa, T., Ogasawara, Y., Hama, Y., Lang, H., Noda, N. N., Suzuki, K.
10.1101/2025.03.27.645728 — Posted: 2025-03-28 — Discussion: 2025-06-05  Review Commons
Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans
Xiang, Y., Tanwar, V., singh, P., La Follette, L., Kapahi, P.
10.1101/2024.09.23.24314197 — Posted: 2024-09-24 — Discussion: 2025-06-05  eLife
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Wu, Y., Guo, W., Kuang, H., Wu, X., Wang, Y., Zhao, S., Yu, T.
10.1101/2023.12.14.570333 — Posted: 2023-12-14 — Discussion: 2025-06-04  eLife
The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the gut
Zhang, Y., Li, Y., Noya, S. B., Sehgal, A.
10.1101/2024.02.29.582770 — Posted: 2024-02-29 — Discussion: 2025-06-04  eLife
Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism
Tubert, C., Paz, R. M., Stahl, A. M., Rela, L., Murer, M. G.
10.1101/2024.05.31.596877 — Posted: 2024-06-01 — Discussion: 2025-06-04  eLife

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