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Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
Arifova, L., MacTavish, B. S., Laughlin, Z., Karadi Girdhar, M. N., Shang, J., Li, M.-H., Yu, X., Zhu, D., Kamenecka, T. M., Kojetin, D.
10.1101/2025.03.04.640448 — Posted: 2025-03-05 — Discussion: 2025-05-08  eLife
Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
Ishchenko, Y., Jeng, A. T., Feng, S., Nottoli, T., Manriquez-Rodriguez, C., Nguyen, K., Carrizales, M. G., Vitarelli, M. J., Corcoran, E. E., Greer, C. A., Myers, S. A., Koleske, A. J.
10.1101/2024.01.05.574442 — Posted: 2024-01-06 — Discussion: 2025-05-07  eLife
Magnetically Steered Cell Therapy For Functional Restoration Of Intraocular Pressure Control In Open-Angle Glaucoma
Bahrani Fard, M. R., Chan, J., Read, A. T., Li, G., Cheng, L., N Safa, B., Siadat, S. M., Jhunjhunwala, A., Grossniklaus, H. E., Emelianov, S. Y., Stamer, W. D., Kuehn, M. H., Ethier, C. R.
10.1101/2024.05.13.593917 — Posted: 2024-05-15 — Discussion: 2025-05-07  eLife
Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI
Autio, J. A., Kimura, I., Ose, T., Matsumoto, Y., Ohno, M., Urushibata, Y., Ikeda, T., Glasser, M. F., Van Essen, D. C., Hayashi, T.
10.1101/2024.05.16.594068 — Posted: 2024-05-17 — Discussion: 2025-05-07  eLife
Unravelling the neurocognitive mechanisms underlying counterconditioning in humans
Wirz, L., Houtekamer, M. C., de Vos, J., Dunsmoor, J. E., Homberg, J., Henckens, M. J. A. G., Hermans, E.
10.1101/2024.07.29.605706 — Posted: 2024-07-30 — Discussion: 2025-05-07  eLife
Heritability of movie-evoked brain activity and connectivity
Gruskin, D. C., Vieira, D. J., Lee, J. K., Patel, G. H.
10.1101/2024.09.16.612469 — Posted: 2024-09-16 — Discussion: 2025-05-07  eLife
Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers
Leong, M. L., Ruedl, C., Karjalainen, K.
10.1101/2024.11.22.624913 — Posted: 2024-11-25 — Discussion: 2025-05-07  eLife
Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster.
Bertran-Mas, J., De Giorgio, E., Martin, N., Llimargas, M.
10.1101/2024.12.02.626067 — Posted: 2024-12-02 — Discussion: 2025-05-07  Review Commons
Monocyte-derived macrophage recruitment mediated by TRPV1 is required for eardrum wound healing
Zhang, Y., Wang, P., Neng, L., Sharma, K., Kachelmeier, A., shi, x.
10.1101/2025.02.03.635565 — Posted: 2025-02-03 — Discussion: 2025-05-07  eLife
Iron-deplete diet enhances Caenorhabditis elegans lifespan via oxidative stress response pathways
Das, P., Ravi, R., Singh, J.
10.1101/2025.02.11.637611 — Posted: 2025-02-15 — Discussion: 2025-05-07  Review Commons

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