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Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A
Cardno, A., Roberts, K., Lindon, C.
10.1101/2025.04.23.650020 — Posted: 2025-04-23 — Discussion: 2025-12-31  eLife
The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring
Hisler, V., Rees, L., Blanchoud, S., Lischer, H. E. L., Bruggmann, R., Jazwinska, A.
10.1101/2025.09.23.678041 — Posted: 2025-09-25 — Discussion: 2025-12-31  eLife
Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes
Li, L., Hunter, S., Leach, S., Zhuang, Y., Liu, H., Gao, J., Zhang, Q., Stasevich, T. J., Kimura, H., Dowell, R. D., Zhang, G.
10.1101/2025.10.08.681188 — Posted: 2025-10-11 — Discussion: 2025-12-31  eLife
SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path
Yamauchi, M., Brandani, G. B., Terakawa, T., Takada, S.
10.1101/2024.04.29.591782 — Posted: 2024-05-02 — Discussion: 2025-12-30  eLife
The Drosophila EGF domain protein Uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch
Baldenius, M., Kautzmann, S., Kottmeier, R., Klämbt, C.
10.1101/2025.01.02.631076 — Posted: 2025-01-02 — Discussion: 2025-12-30  eLife
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Weir, K., Lyu, P., Kandoi, S., An, R., Pannullo, N., Palaxxo, I., Tangeman, J., Shi, J., DeVries, S., Merriman, D., Qian, J., Blackshaw, S.
10.1101/2025.04.25.650540 — Posted: 2025-04-29 — Discussion: 2025-12-30  eLife
Targeted Computational Design of an Interleukin-7 Superkine with Enhanced Folding Efficiency and Immunotherapeutic Efficacy
Lim, S.-K., Lin, W.-C., Pan, Y.-C., Huang, S.-W., Yu, Y.-A., Chang, C.-H., Hu, C.-M. J., Mou, C.-Y., Mou, K. Y.
10.1101/2025.06.03.657627 — Posted: 2025-06-06 — Discussion: 2025-12-30  eLife
Squidly: Enzyme Catalytic Residue Prediction Harnessing a Biology-Informed Contrastive Learning Framework
Rieger, W. J., Boden, M., Arnold, F. H., Mora, A.
10.1101/2025.06.13.659624 — Posted: 2025-06-20 — Discussion: 2025-12-30  eLife
Male-Biased Cyp17a2 Governs Antiviral Sexual Dimorphism in Fish via STING Stabilization and Viral Protein Degradation
Lu, L.-F., Cui, B.-j., Shi, S.-C., Wang, Y.-Y., Zhang, C., Xu, X., Tian, M.-Z., Li, Z.-Q., Xu, N., Li, Z.-C., Chen, D.-D., Zhou, L., Zhai, G., Yin, Z., Li, S.
10.1101/2025.06.23.661124 — Posted: 2025-06-27 — Discussion: 2025-12-30  eLife
Perceptual predictions track subjective, over objective, statistical structure
Clarke, J., Rittershofer, K., Ward, E. K., Yon, D., Press, C.
10.1101/2025.07.30.667172 — Posted: 2025-07-31 — Discussion: 2025-12-30  eLife

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