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Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells
Zhang, Q., Wang, Y., Fu, X., Wang, Z., Zhang, Y., Yan, L., Wang, Y., Yang, M., Song, D., Zhang, R., Zhang, H., Wu, S., Zhao, S.
10.1101/2025.04.17.649440 — Posted: 2025-04-23 — Discussion: 2026-02-19  eLife
Mycobacterial Metallophosphatase MmpE Acts as a Nucleomodulin to Regulate Host Gene Expression and Promote Intracellular Survival
Chen, L., Duan, B., Jiang, Q., Wang, Y., Chen, Y., Zhang, L., Guo, A.
10.1101/2025.06.24.661236 — Posted: 2025-06-24 — Discussion: 2026-02-19  eLife
Cul5Wsb2 uses BCL2 proteins as co-receptors to target Bim for degradation.
Vaysse-Zinkhofer, W., Alcindor, E., Garaffo, N., Toczyski, D. P.
10.1101/2025.08.14.670414 — Posted: 2025-08-14 — Discussion: 2026-02-19  eLife
Multi-barrier unfolding of the double-knotted protein, TrmD-Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics
Bruno da Silva, F., Niewieczerzal, S., Lewandowska, I., Sikora, M., Silbermann, L.-M., Tych, K. M., Sulkowska, J. I.
10.1101/2025.08.27.672562 — Posted: 2025-08-29 — Discussion: 2026-02-19  eLife
Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation
Cui, J., Fan, Z., Ding, S., Zhang, J., Shen, H., Zaidi, S. A., Ding, Y.
10.1101/2025.09.10.675441 — Posted: 2025-09-16 — Discussion: 2026-02-19  eLife
Transition of Staphylococcus aureus tetracycline resistance plasmid pT181 from independent multicopy replicon to predominantly integrated chromosomal element over 65 years
Phillips, M. A., Petit, R. A., Weissman, D. B., Read, T. D.
10.1101/2025.09.14.675889 — Posted: 2025-09-15 — Discussion: 2026-02-19  eLife
PSD-95 drives binocular vision maturation critical for predation
Bhattacharya, S., Versprille, L. J. F. W., Schoene, C., Schlueter, O. M., Loewel, S.
10.1101/2025.10.22.683936 — Posted: 2025-10-23 — Discussion: 2026-02-19  eLife
A translational transcriptomic signature of vaccine reactogenicity for the evaluation of novel formulations
Becker, J., Roelens, M., Reynaud, K., Beloeil, L.
10.1101/2025.11.20.689650 — Posted: 2025-11-25 — Discussion: 2026-02-19  eLife
Synaptotagmin-7 is required for synchronous but not asynchronous facilitation of glutamate release at cortical boutons
Kotzadimitriou, D., Langley, H., McGowan, E., R.F. Mendonca, P., Tagliatti, E., Timofeeva, Y., Krishnakumar, S. S., Volynski, K. E.
10.64898/2025.12.19.695358 — Posted: 2025-12-22 — Discussion: 2026-02-19  eLife
Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention
Philpot, B., James, L. M., Friar, C. A., Liang, S., Gao, E. B., Burette, A. C.
10.64898/2025.12.23.696277 — Posted: 2025-12-24 — Discussion: 2026-02-19  eLife

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