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Predicting the effect of CRISPR-Cas9-based epigenome editing
Batra, S. S., Cabrera, A., Spence, J. P., Hilton, I., Song, Y. S.
10.1101/2023.10.03.560674 — Posted: 2023-10-03 — Discussion: 2025-05-23  eLife
p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
Brdar, A., Osterburg, C., Münick, P., Machel, A. C., Rathore, R., Osterburg, S., Yüksel, B., Schäfer, B., Desch, K., Langer, J. D., Dikic, I., Dötsch, V.
10.1101/2024.10.02.616239 — Posted: 2024-10-06 — Discussion: 2025-05-23  eLife
Neocortical Layer-5 tLTD Relies on Non-Ionotropic Presynaptic NMDA Receptor Signaling
Thomazeau, A., Rannio, S., Brock, J. A., Wong, H. H.-W., Sjöström, P. J.
10.1101/2025.02.07.637179 — Posted: 2025-02-10 — Discussion: 2025-05-23  eLife
The ESCRT protein CHMP5 restrains skeletal progenitor cell senescence by preserving endo-lysosomal-mitochondrial network
Ge, X., He, L., Liu, H., Haynes, C. M., Shim, J.-H.
10.1101/2020.08.03.233874 — Posted: 2020-08-04 — Discussion: 2025-05-22  eLife
Somatic hypermutation spectra are independent of the local transcriptional and epigenetic landscape
Schoeberl, U. E., Fitz, J., Froussios, K., Valieris, R., Makharova, M., Ourailidis, I., Bauer, B., Neumann, T., Wiedemann, E.-M., Steininger, M., Garcia, A. C., Mastrovito, M., Mouquet, H., Silva, I., Pavri, R.
10.1101/2022.05.21.492925 — Posted: 2022-05-21 — Discussion: 2025-05-22  eLife
Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells
Dehghannasiri, R., Henderson, G., Bierman, R., Chaung, K., Baharav, T. Z., Wang, P. L., Salzman, J.
10.1101/2022.12.06.519414 — Posted: 2022-12-07 — Discussion: 2025-05-22  eLife
Hypothermia protects against ventilator-induced lung injury by limiting IL-1beta release and NETs formation
Nosaka, N., Borges, V., Martinon, D., Crother, T. R., Arditi, M., Shimada, K.
10.1101/2024.09.02.610778 — Posted: 2024-09-03 — Discussion: 2025-05-22  eLife
Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction
Guo, W., Tian, L., Chu, D., Shu, W., Benton, M., Liu, J., Tong, J.
10.1101/2024.11.17.624019 — Posted: 2024-11-18 — Discussion: 2025-05-22  eLife
Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
Yu, X., He, Y., Kamenecka, T. M., Kojetin, D. J.
10.1101/2025.03.19.642122 — Posted: 2025-03-19 — Discussion: 2025-05-22  eLife
Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IkappaBalpha without requiring ATP
Polley, S., Borar, P., Biswas, T., Huxford, T., Ghosh, G.
10.1101/2023.06.27.546692 — Posted: 2023-06-27 — Discussion: 2025-05-21  eLife

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