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On the path to reference genomes for all biodiversity: lessons learned and laboratory protocols created in the Sanger Tree of Life core laboratory over the first 2000 species
Howard, C., Denton, A., Jackson, B., Bates, A., Jay, J., Yatsenko, H., Raman, P. S., Thomas, A., Oatley, G., do Amaral, R. V., Göktan, Z. E., Gomez, J. P. N., Clayton Lucey, I., Sinclair, E., Quail, M. A., Blaxter, M., Howe, K., Lawniczak, M.
10.1101/2025.04.11.648334 — Posted: 2025-04-11 — Discussion: 2025-10-30  GigaScience
Ubiquitous systems drift in the evolution of development
van der Jagt, P. L., Oud, S., Vroomans, R. M. A.
10.1101/2025.04.23.650280 — Posted: 2025-04-23 — Discussion: 2025-10-30  Review Commons
Conduction pathway for potassium through the E. coli pump KdpFABC
Hussein, A., Zhang, X., P. Pedersen, B., Stokes, D. L.
10.1101/2025.05.05.652293 — Posted: 2025-05-06 — Discussion: 2025-10-30  eLife
Insights from aquaporin structures into drug-resistant sleeping sickness
Matusevicius, M., Corey, R. A., Gragera, M., Yamashita, K., Sprenger, T., Ungogo, M., Blaza, J. N., Castro-Hartmann, P., Chirgadze, D. Y., Chaitanya Vedithi, S., Afanasyev, P., Melero, R., Warshamanage, R., Gusach, A., Carazo, J.-M., Carrington, M., Blundell, T., Murshudov, G. N., Stansfeld, P. J., Sansom, M. S., De Koning, H. P., Tate, C. G., Weyand, S.
10.1101/2025.05.15.654314 — Posted: 2025-05-17 — Discussion: 2025-10-30  eLife
Ultra-deep long-read metagenomics captures diverse taxonomic and biosynthetic potential of soil microbes
Bagci, C., Negri, T., Buena-Atienza, E., Gross, C., Ossowski, S., Ziemert, N.
10.1101/2025.05.28.656579 — Posted: 2025-05-28 — Discussion: 2025-10-30  GigaScience
The enduring advantages of the SLOW5 file format for raw nanopore sequencing data
Gamaarachchi, H., Jenner, S., Samarakoon, H., Ferguson, J. M., Deveson, I. W.
10.1101/2025.06.30.662478 — Posted: 2025-07-04 — Discussion: 2025-10-30  GigaScience
Genomic and epidemiologic characteristics of SARS-CoV-2 persistent infections in California, January 2021 - July 2023
Bell, J. M., Elder, J., Ryder, R., Smith, E. A., Scribner, M., Gilliam, S., Borthwick, D., Crumpler, M., Skarbinski, J., Morales, C., Wadford, D. A.
10.1101/2025.07.14.664650 — Posted: 2025-07-16 — Discussion: 2025-10-30  
Nucleosome Positioning Shapes Cryptic Antisense Transcription
Kok, J. Y., Harvey, Z. H., Axelsson, E., Berger, F.
10.1101/2025.07.14.664753 — Posted: 2025-07-18 — Discussion: 2025-10-30  Review Commons
EssSubgraph improves performance and generalizability of mammalian essential gene prediction with large networks
wen, h., Carpenter, S., McGinnis, K., Nelson, A., Smith, K., hong, t.
10.1101/2025.07.21.665218 — Posted: 2025-07-25 — Discussion: 2025-10-30  GigaScience
Redox Dyshomeostasis Links Renal and Neuronal Dysfunction in Drosophila Models of Gaucher and Parkinson's Disease
Hull, A. J., Atilano, M. L., Kinghorn, K. J.
10.1101/2025.08.06.668868 — Posted: 2025-08-09 — Discussion: 2025-10-30  eLife

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