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8,541 Reviews — eLife — All Subjects

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Permissive and instructive Hox codes govern limb positioning

Wang, Y., Hintze, M., Wang, J., Petzsch, P., Kohrer, K., Tao, H., Cheng, L., Zhou, P., Wang, J., Liao, Z., Qi, X.-F., Cai, D., Bartolomaeus, T., Schilling, K., Wilting, J., Kuerten, S., Koentges, G., Patel, K., Pu, Q., Huang, R.

10.1101/2024.07.15.603511 — Posted: 2024-07-19 — Discussion: 2026-01-19 eLife

p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration

Kumar, R., Couly, S., Muys, B. R., Li, X. L., Grammatikakis, I., Singh, R., Guest, M., Wen, X., Tang, W., Ambs, S., Jenkins, L. M., Pehrsson, E. C., Chari, R., Su, T.-P., Lal, A.

10.1101/2025.05.12.653341 — Posted: 2025-05-13 — Discussion: 2026-01-19 eLife

Specific GPCRs Elicit Unique Extracellular Vesicle MiRNA Array Signatures: An Exploratory Study

Shi, X., Palumbo, M. C., Benware, S., Wiedrick, J., Markwardt, S., Janowsky, A. J.

10.1101/2025.06.16.659918 — Posted: 2025-06-20 — Discussion: 2026-01-19 eLife

The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers

Koulle, A., Ogundele, O., Shah, D., Baker, I., Lopez, M., Reynolds, N., Ragheb, R., Laue, E. D., Hendrich, B.

10.1101/2025.08.29.672645 — Posted: 2025-08-29 — Discussion: 2026-01-19 eLife

Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage

Huang, Z., Luo, S., Wang, Z., Zhang, Z., Jiang, B., Nie, Q., Zhang, J.

10.1101/2024.07.10.602845 — Posted: 2024-07-12 — Discussion: 2026-01-16 eLife

Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease

Graff, M. F. E., Heeg, E. E., Childs, S. J.