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Predicting the effect of CRISPR-Cas9-based epigenome editing
Batra, S. S., Cabrera, A., Spence, J. P., Hilton, I., Song, Y. S.
10.1101/2023.10.03.560674 — Posted: 2023-10-03 — Discussion: 2025-05-23  eLife
Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation
Twardowski, J. J., Heist, T. I., Soares, Z. G., Berry, E. S., Ruffolo, L. I., Proschel, C., Mello, S. S.
10.1101/2024.05.29.595146 — Posted: 2024-06-02 — Discussion: 2025-05-23  Review Commons
p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
Brdar, A., Osterburg, C., Münick, P., Machel, A. C., Rathore, R., Osterburg, S., Yüksel, B., Schäfer, B., Desch, K., Langer, J. D., Dikic, I., Dötsch, V.
10.1101/2024.10.02.616239 — Posted: 2024-10-06 — Discussion: 2025-05-23  eLife
Lipid-driven SRC self-association modulates its transformation capacity
Mohammad Jabeen, I.-L., Giannotti, M., Fourgous, E., Boublik, Y., Fernandez, A., Le Roux, A.-L., Sirvent, A., Taules, M., roche, s., Pons, M.
10.1101/2024.11.12.623151 — Posted: 2024-11-12 — Discussion: 2025-05-23  EMBO Press
Neocortical Layer-5 tLTD Relies on Non-Ionotropic Presynaptic NMDA Receptor Signaling
Thomazeau, A., Rannio, S., Brock, J. A., Wong, H. H.-W., Sjöström, P. J.
10.1101/2025.02.07.637179 — Posted: 2025-02-10 — Discussion: 2025-05-23  eLife
Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease
Graff, M. F. E., Heeg, E. E., Childs, S. J.
10.1101/2025.03.13.643043 — Posted: 2025-03-13 — Discussion: 2025-05-23  eLife
GMCL1 Controls 53BP1 Stability and Modulates Paclitaxel Sensitivity in Cancer
KITO, Y., Gonzalez-Robles, T. J., Kaisari, S., Pae, J., Garcia, S. F., Ortiz-Pacheco, J., Ueberheide, B., Lehmann, R., Marzio, A., Rona, G., Pagano, M.
10.1101/2025.03.18.643855 — Posted: 2025-03-20 — Discussion: 2025-05-23  eLife
The ESCRT protein CHMP5 restrains skeletal progenitor cell senescence by preserving endo-lysosomal-mitochondrial network
Ge, X., He, L., Liu, H., Haynes, C. M., Shim, J.-H.
10.1101/2020.08.03.233874 — Posted: 2020-08-04 — Discussion: 2025-05-22  eLife
Somatic hypermutation spectra are independent of the local transcriptional and epigenetic landscape
Schoeberl, U. E., Fitz, J., Froussios, K., Valieris, R., Makharova, M., Ourailidis, I., Bauer, B., Neumann, T., Wiedemann, E.-M., Steininger, M., Garcia, A. C., Mastrovito, M., Mouquet, H., Silva, I., Pavri, R.
10.1101/2022.05.21.492925 — Posted: 2022-05-21 — Discussion: 2025-05-22  eLife
Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells
Dehghannasiri, R., Henderson, G., Bierman, R., Chaung, K., Baharav, T. Z., Wang, P. L., Salzman, J.
10.1101/2022.12.06.519414 — Posted: 2022-12-07 — Discussion: 2025-05-22  eLife

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