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An ATM-MYBL2-CDC7 axis regulates replication initiation and prevents replication stress in pluripotent stem cells
Blakemore, D., Almaghrabi, R., Vilaplana, N., Gonzalez, E., Moya, M., Murphy, G., Stewart, G., Gambus, A., Petermann, E., Garcia, P.
10.1101/2020.06.04.131276 — Posted: 2020-06-05 — Discussion: 2021-04-13  EMBO Press
Chance, contingency, and necessity in the experimental evolution of ancestral proteins
Xie, V. C., Pu, J., Metzger, B. P. H., Thornton, J. W., Dickinson, B.
10.1101/2020.08.29.273581 — Posted: 2020-08-29 — Discussion: 2021-04-12  eLife
Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction
Subramanian, S., Gorday, K., Marcus, K., Orellana, M. R., Ren, P., Luo, X. R., O'Donnell, M. E., Kuriyan, J.
10.1101/2020.12.31.424921 — Posted: 2021-01-02 — Discussion: 2021-04-12  eLife
Widespread bacterial protein flavinylation in functionally distinct extracytosolic redox biochemistries
Méheust, R., Huang, S., Rivera-Lugo, R., Banfield, J., Light, S. H.
10.1101/2021.01.07.425746 — Posted: 2021-01-07 — Discussion: 2021-04-12  eLife
Visualizing endogenous RhoA activity with an improved localization-based, genetically encoded biosensor
Mahlandt, E. K., Arts, J. J. G., van der Meer, W. J., van der Linden, F. H., Tol, S., van Buul, J. D., Gadella, T. W. J., Goedhart, J.
10.1101/2021.02.08.430250 — Posted: 2021-02-08 — Discussion: 2021-04-12  Review Commons
Differential Conditioning Produces Merged Long-term Memory in Drosophila
Zhao, B., Sun, J., Li, Q., Zhong, Y.
10.1101/2021.01.13.426486 — Posted: 2021-01-14 — Discussion: 2021-04-09  eLife
7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome
Tomita, H., Hines, K. M., Herron, J. M., Li, A., Baggett, D. W., Xu, L.
10.1101/2021.01.30.428955 — Posted: 2021-02-01 — Discussion: 2021-04-09  eLife
Towards deciphering the Nt17 code: How the sequence and conformation of the first 17 amino acids in Huntingtin regulate the aggregation, cellular properties, and neurotoxicity of mutant Httex1
Vieweg, S., Mahul-Mellier, A.-L., Ruggeri, F. S., Riguet, N., DeGuire, S. M., Chiki, A., Cendrowska, U., Dietler, G., Lashuel, H. A.
10.1101/2021.02.15.431207 — Posted: 2021-02-16 — Discussion: 2021-04-09  Review Commons
A Bitopic Miniprotein Regulates a Membrane-Embedded Enzyme via Topological Allostery
Weber, D. K., Hernandez, M. S., Reddy, V. U., Wang, S., Larsen, E. K., Tata, G., Gustavsson, M., Cornea, R. L., Thomas, D. D., De Simone, A., Veglia, G.
10.1101/2020.08.28.271940 — Posted: 2020-08-28 — Discussion: 2021-04-08  eLife
Diversity of excitatory release sites
Karlocai, R. R., Heredi, J., Benedek, T., Holderith, N., Lorincz, A., Nusser, Z.
10.1101/2021.02.15.431316 — Posted: 2021-02-16 — Discussion: 2021-04-08  eLife

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