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7,800 Reviews — eLife — All Subjects

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Niche homeostasis in multi-lineage stem cell populations is maintained through intercellular redox gradients
Majhi, O., Chhatre, A., Chaudhary, T., Sinha, D.
10.1101/2023.12.06.570086 — Posted: 2023-12-06 — Discussion: 2025-12-31  eLife
Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model
Wang, P.-K., Lin, K.-h., Tang, T. K.
10.1101/2024.06.17.598507 — Posted: 2024-06-20 — Discussion: 2025-12-31  eLife
Shifting the PPARγ conformational ensemble towards a transcriptionally repressive state improves covalent inhibitor efficacy
Arifova, L., MacTavish, B. S., Laughlin, Z., Karadi Girdhar, M. N., Shang, J., Li, M.-H., Yu, X., Zhu, D., Kamenecka, T. M., Kojetin, D.
10.1101/2025.03.04.640448 — Posted: 2025-03-05 — Discussion: 2025-12-31  eLife
Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A
Cardno, A., Roberts, K., Lindon, C.
10.1101/2025.04.23.650020 — Posted: 2025-04-23 — Discussion: 2025-12-31  eLife
Differential Regulation of Hepatic Macrophage Fate by Chi3l1 in MASLD
He, J., Chen, B., Wang, X., Yang, R., Deng, C., Zhu, X., Wang, K., Wang, L., Lu, X., Peng, C., Li, C., Shan, Z.
10.1101/2025.05.06.652369 — Posted: 2025-05-06 — Discussion: 2025-12-31  eLife
Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal
Balasubramanian, R., Tolman, N., Li, T., Hannan, A., Bupp-Chickering, V., Polanco, K., Bhandari, A., Zhou, S., Simon, M., Peregrin, J., Montgomery, C., Kizhatil, K., Qian, J., John, S.
10.1101/2025.08.15.670438 — Posted: 2025-08-21 — Discussion: 2025-12-31  eLife
PH sensitivity of cerebrospinal fluid-contacting neurons involves the modulation of phasic and tonic currents mediated by PKD2L1 channels located in the apical process.
Vitar, M., Prieto, D., Malas, S., Russo, R. E., Trigo, F. F.
10.1101/2025.08.24.671961 — Posted: 2025-08-27 — Discussion: 2025-12-31  eLife
Earliest Evidence of Elephant Butchery at Olduvai Gorge (Tanzania) Reveals the Evolutionary Impact of Early Human Megafaunal Exploitation
Dominguez-Rodrigo, M., Baquedano, E., Moclan, A., Uribelarrea, D., Velazquez-tello, A., Corre-Cano, J. A., Diez-Martin, F., Organista, E., Mendez-Quintas, E., Vegara-Riquelme, M., Gidna, A., Mabulla, A.
10.1101/2025.08.28.672811 — Posted: 2025-08-28 — Discussion: 2025-12-31  eLife
A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis
Xu, T., Cao, F., Zhou, R., Chen, Q., Zhong, J., Wang, Y., Xiao, C., Yin, B., Chen, C., Zhao, C.
10.1101/2025.08.29.673025 — Posted: 2025-09-03 — Discussion: 2025-12-31  eLife
A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage
Moss, T., Wooldredge, A., Bhakta, K., Cronin, M., Gestwicki, J. E., Mukherjee, S.
10.1101/2025.09.05.672953 — Posted: 2025-09-06 — Discussion: 2025-12-31  eLife

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