Channel:  Francis Crick Institute

1,122 Articles

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets
Bennett, J. M., Narwal, S. K., Kabeche, S., Abegg, D., Hackett, F., Yeo, T., Li, V., Muir, R. K., Faucher, F. F., Lovell, S., Blackman, M., Adibekian, A., Yeh, E., Fidock, D. A., Bogyo, M.
10.1101/2024.01.11.575224 — Posted: 2024-01-11
Cell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function
Diffley, J., Lim, C. T., Miller, T. C., Tan, K. W., Talele, s., Early, A., East, P., Sanchez, H., Dekker, N. H., Costa, A.
10.1101/2024.01.10.575016 — Posted: 2024-01-10
Oncogenic PIK3CA corrupts growth factor signaling specificity
Madsen, R. R., Le Marois, A., Mruk, O., Voliotis, M., Yin, S., Sufi, J., Qin, X., Zhao, S. J., Gorczynska, J., Morelli, D., Davidson, L., Sahai, E., Korolchuk, V. I., Tape, C. J., Vanhaesebroeck, B.
10.1101/2023.12.23.573207 — Posted: 2023-12-26
Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice
King, A., Reichl, P., Metson, J. S., Parker, R., Munro, D., Oliveira, C., Becker, J. R., Biggs, D., Preece, C., Davies, B., Chapman, J. R.
10.1101/2023.12.20.572534 — Posted: 2023-12-21
Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M., Bentham, R. B., Henriques, T., Ng, S. Q., Ren, Z., Esculier, C., Agarwal, S., Tong, E., Ilangovan, S., Szabadkai, Z., Suman, M., Patani, N., Ghanate, A., Bryson, K., Stein, R. C., Yuneva, M., Szabadkai, G.
10.1101/2023.02.17.528922 — Posted: 2023-12-21
RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
Fu, B., Brock, E. E., Andrews, R., Breiter, J. C., Tian, R., Toomey, C. E., Lachica, J., Lashley, T., Ryten, M., Wood, N. W., Vendruscolo, M., Gandhi, S., Weiss, L. E., Beckwith, J. S., Lee, S. F.
10.1101/2023.12.18.572148 — Posted: 2023-12-19
The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
Timimi, L., Wrobel, A. G., Chiduza, G. N., Maslen, S. L., Torres-Mendez, A., Montaner, B., Davis, C., Skehel, M., Rubinstein, J. L., Schreiber, A. L., Beale, R.
10.1101/2023.12.19.572309 — Posted: 2023-12-19
Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography
Greenwood, H. E., Edwards, R. S., Tyrrell, W. E., Barber, A. R., Baark, F., Tanc, M., Khalil, E., Falzone, A., Ward, N. P., DeBlasi, J. M., Torrente, L., Pearce, D. R., Firth, G., Smith, L. M., Vilhelmsson Timmermand, O., Huebner, A., George, M. E., Swanton, C., Hynds, R. E., DeNicola, G. M., Witney, T. H.
10.1101/2023.12.16.572007 — Posted: 2023-12-17
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation
Bertran, M. T., Walmsley, R., Cummings, T. F. M., Aramburu, I., Benton, D. J., Assalaarachchi, J., Chasampalioti, M., Swanton, T., Joshi, D., Federico, S., Okkenhaug, H., Yu, L., Oxley, D., Walker, S., Papayannopoulos, V., Suga, H., Christophorou, M. A., Walport, L. J.
10.1101/2023.12.12.571217 — Posted: 2023-12-12
Brain-wide activity-identity mapping of neural networks associated with prosocial motivation in rats
Ruzal, K., Trachtenberg, E., Kantor, B., Flumin, H., Roemer, A., Crespo, A., Kohl, J., Ben-Ami Bartal, I.
10.1101/2023.12.10.570980 — Posted: 2023-12-11

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