Channel:  Francis Crick Institute

1,122 Articles

Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response
Jones, R. A., Cooper, F., Kelly, G., Barry, D., Renshaw, M. J., Sapkota, G., Smith, J. C.
10.1101/2024.02.10.579757 — Posted: 2024-02-12
Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications
Matwani, K., Cornish, J., DeBenedictis, E. A., Heller, G. T.
10.1101/2024.02.12.579991 — Posted: 2024-02-12
Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia
Rahman, S., Bloye, G., Farah, N., Demeulemeester, J., Costa, J. R., O'Connor, D., Pocock, R., Turna, A., Wang, L., Lee, S., Fielding, A. K., Roels, J., Jaksik, R., Dawidowska, M., Vlierberghe, P. V., Hadjur, S., Hughes, J. R., Davies, J. O. J., Gutierrez, A., Kelliher, M. A., Loo, P. V., Dawson, M. A., Mansour, M. R.
10.1101/2024.02.06.579027 — Posted: 2024-02-08
Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1
Griffith, S., Muir, L., Suchanek, O., Hope, J., Pade, C., Gibbons, J. M., Tuong, Z. K., Fung, A., Touizer, E., Rees-Spear, C., Nans, A., Roustan, C., Alguel, Y., Fink, D., Orkin, C., Deayton, J., Anderson, J., Gupta, R. K., Doores, K. J., Cherepanov, P., McKnight, A., Clatworthy, M., McCoy, L. E.
10.1101/2024.02.05.578789 — Posted: 2024-02-06
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
Koussis, K., Haase, S., Withers-Martinez, C., Flynn, H. R., Kunzelmann, S., Christodoulou, E., Ibrahim, F., Skehel, M., Baker, D. A., Blackman, M. J.
10.1101/2024.02.04.578801 — Posted: 2024-02-04
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Simon, C. S., McCarthy, A., Woods, L., Staneva, D., Huang, Q., Linneberg-Agerholm, M., Faulkner, A., Papathanasiou, A., Elder, K., Snell, P., Christie, L., Garcia, P., Shaikly, V., Taranissi, M., Choudhary, M., Herbert, M., Brickman, J. M., Niakan, K. K.
10.1101/2024.02.01.578414 — Posted: 2024-02-04
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation
Klein, P., Harley, J., Crook, H., Serna, S. E., Petric-Howe, M., Roumeliotis, T. I., Choudhary, J. S., Chakrabarti, A. M., Luisier, R., Patani, R., Ramos, A.
10.1101/2023.09.12.557394 — Posted: 2024-02-02
Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size
Chu, L.-Y., Stedman, D., Gannon, J., Cox, S., Pobegalov, G., Molodtsov, M.
10.1101/2024.02.01.578443 — Posted: 2024-02-02
Combining RASG12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot
Anastasiou, P., Moore, C., Rana, S., de Castro, A., Tomaschko, M., Boumelha, J., Mugarza, E., Blaj, C., de Carne Trecesson, S., Goldstone, R., Smith, J., Quintana, E., Molina-Arcas, M., Downward, J.
10.1101/2024.01.15.575765 — Posted: 2024-01-30
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir
Dinh, T., Tber, Z., Rey, J. S., Mengshetti, S., Annamalai, A. S., Haney, R., Briganti, L., Amblard, F., Fuchs, J. R., Cherepanov, P., Kim, K., Schinazi, R. F., Perilla, J. R., Kim, B., Kvaratskhelia, M.
10.1101/2024.01.26.577387 — Posted: 2024-01-26

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