Channel:  Francis Crick Institute

1,139 Articles

p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
Wittke, C. I., Cheung, E. C., Athineos, D., Clements, N., Butler, L., Hughes, M., Morrison, V., Watt, D., Blyth, K., Vousden, K., Humpton, T. J.
10.1101/2024.05.20.594983 — Posted: 2024-05-21
Imaging of MAP kinase dynamics reveals endocytic regulation of pulsatile signalling and network re-wiring in response to targeted therapy in EGFR-mutant non-small cell lung cancer
Le Marois, A. M. I., Bailey, S., Hooper, S., Kumar, S., Sparks, H., Alexandrov, Y., Caswell, D. R., Fröhlich, F., Schlegelmilch, K., Valand, K., Martin, M. J., Narvaez, A. J., Swanton, C., Downward, J., Dunsby, C., French, P. M., Sahai, E.
10.1101/2024.05.14.594112 — Posted: 2024-05-17
Deep proteomic analysis of human microglia and model systems reveal fundamental biological differences of in vitro and ex vivo cells
Lloyd, A. F., Martinez-Muriana, A., Davis, E., Daniels, M. J., Hou, P., Mancuso, R., Brenes-Murillo, A. J., Geric, I., Snellinx, A., Craessaerts, K., Theys, T., Fiers, M., De Strooper, B., Howden, A. J.
10.1101/2022.07.07.498804 — Posted: 2024-05-16
An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast
Libby, A. R., Rito, T., Radley, A., Briscoe, J.
10.1101/2024.05.16.594506 — Posted: 2024-05-16
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2
Bashore, F. M., Min, S. M., Chen, X., Howell, S., Rinderle, C. H., Morel, G., Silvaroli, J. A., Wells, C. I., Bunnell, B. A., Drewry, D., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Axtman, A. D.
10.1101/2024.05.12.593776 — Posted: 2024-05-14
An image segmentation method based on the spatial correlation coefficient of Local Moran's I - identification of A-type potassium channel clusters in the thalamus.
David, C., Giber, K., Kerti-Szigeti, K., Kollo, M., Nusser, Z., Acsady, L.
10.1101/2023.05.02.539063 — Posted: 2024-05-10
Spatiotemporal Orchestration of Mitosis by Cyclin-Dependent Kinase
Kapadia, N., Nurse, P.
10.1101/2024.04.29.591629 — Posted: 2024-04-30
The Streptococcus pneumoniae transcriptome in patient cerebrospinal fluid identifies novel virulence factors required for meningitis
Wall, E. C., Guerra-Assuncao, J.-A., Yang, M., Konig, R., Audshasai, T., Proust, A., Aprianto, R., Ramos-Sevillano, E., Ercoli, G., Bordin, N., Agostinho-Terra, V. S., Veening, J.-W., Lalloo, D. G., Wren, B. W., Wilkinson, R. J., Brouwer, M. C., van de Beek, D., Kadiloglu, A., Heyderman, R. S., Brown, J. S.
10.1101/2024.04.30.591261 — Posted: 2024-04-30
Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis
Khan, M., Hunt, D. M., Singha, B., Kapoor, Y., Singh, N., Prasad, D. V. S., Dharmarajan, S., Sowpati, D. T., de Carvalho, L., Nandicoori, V. K.
10.1101/2023.10.03.560673 — Posted: 2024-04-20
Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1
Dowgier, G., Hobbs, A., Greenwood, D., Shawe-Taylor, M., Stevenson-Leggett, P., Bazire, J., Penn, R., Harvey, R., Libri, V., Kassiotis, G., Gamblin, S., Lewis, N. S., Williams, B., Swanton, C., Gandhi, S., Bauer, D. L., Carr, E. J., Wall, E. C., Wu, M. Y.
10.1101/2024.04.17.589886 — Posted: 2024-04-18

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