Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

1086 Articles

A scaleable inducible knockout systemfor studying essential gene function inthe malaria parasite
Ramaprasad, A., Blackman, M.
10.1101/2024.01.14.575607 — Posted: 2024-01-15
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides
King, H. R., Bycroft, M., Nguyen, T.-B., Kelly, G., Vinogradov, A. A., Rowling, P. J., Stott, K., Ascher, D. B., Suga, H., Itzhaki, L. S., Artavanis-Tsakonas, K.
10.1101/2024.01.11.575158 — Posted: 2024-01-13
Coherent olfactory bulb gamma oscillations arise from coupling independent columnar oscillators
Peace, S. T., Johnson, B. C., Werth, J. C., Li, G., Kaiser, M. E., Fukunaga, I., Schaefer, A. T., Molnar, A. C., Cleland, T. A.
10.1101/213827 — Posted: 2024-01-13
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets
Bennett, J. M., Narwal, S. K., Kabeche, S., Abegg, D., Hackett, F., Yeo, T., Li, V., Muir, R. K., Faucher, F. F., Lovell, S., Blackman, M., Adibekian, A., Yeh, E., Fidock, D. A., Bogyo, M.
10.1101/2024.01.11.575224 — Posted: 2024-01-11
Cell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function
Diffley, J., Lim, C. T., Miller, T. C., Tan, K. W., Talele, s., Early, A., East, P., Sanchez, H., Dekker, N. H., Costa, A.
10.1101/2024.01.10.575016 — Posted: 2024-01-10
Single-cell transcriptional dynamics in a living vertebrate
Eck, E., Moretti, B., Schlomann, B. H., Bragantini, J., Lange, M., Zhao, X., VijayKumar, S., Valentin, G., Loureiro, C., Soroldoni, D., Royer, L. A., Oates, A. C., Garcia, H. H.
10.1101/2024.01.03.574108 — Posted: 2024-01-05
Oncogenic PIK3CA corrupts growth factor signaling specificity
Madsen, R. R., Le Marois, A., Mruk, O., Voliotis, M., Yin, S., Sufi, J., Qin, X., Zhao, S. J., Gorczynska, J., Morelli, D., Davidson, L., Sahai, E., Korolchuk, V. I., Tape, C. J., Vanhaesebroeck, B.
10.1101/2023.12.23.573207 — Posted: 2023-12-26
Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M., Bentham, R. B., Henriques, T., Ng, S. Q., Ren, Z., Esculier, C., Agarwal, S., Tong, E., Ilangovan, S., Szabadkai, Z., Suman, M., Patani, N., Ghanate, A., Bryson, K., Stein, R. C., Yuneva, M., Szabadkai, G.
10.1101/2023.02.17.528922 — Posted: 2023-12-21
Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice
King, A., Reichl, P., Metson, J. S., Parker, R., Munro, D., Oliveira, C., Becker, J. R., Biggs, D., Preece, C., Davies, B., Chapman, J. R.
10.1101/2023.12.20.572534 — Posted: 2023-12-21
RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
Fu, B., Brock, E. E., Andrews, R., Breiter, J. C., Tian, R., Toomey, C. E., Lachica, J., Lashley, T., Ryten, M., Wood, N. W., Vendruscolo, M., Gandhi, S., Weiss, L. E., Beckwith, J. S., Lee, S. F.
10.1101/2023.12.18.572148 — Posted: 2023-12-19

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