Channel:  The Michael J. Fox Foundation

187 Articles

Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
Donzelli, S., OSullivan, S., Mahul-Mellier, A.-L., Ulusoy, A., Fusco, G., Kumar, S. T., Chiki, A., Burtscher, J., Boussouf, M. L. D., Rostami, I., De Simone, A. D. S., Di Monte, D. A., Lashuel, H. A.
10.1101/2023.03.24.534149 — Posted: 2023-03-25
Protein network analysis links the NSL complex to Parkinson's disease and mitochondrial biology
Kelly, K., Lewis, P., Plun-Favreau, H., Manzoni, C.
10.1101/2023.01.27.524249 — Posted: 2023-03-24
Transitions between cognitive topographies: contributions of network structure, neuromodulation, and disease
Luppi, A. I., Singleton, S. P. I., Hansen, J. Y., Bzdok, D., Kuceyeski, A., Betzel, R., Misic, B.
10.1101/2023.03.16.532981 — Posted: 2023-03-17
Lifespan Neurodegeneration Of The Human Brain In Multiple Sclerosis
Coupe, P., Planche, V., Mansencal, B., Kamraoui, R. A., Koubiyr, I., Manjon, J., Tourdias, T.
10.1101/2023.03.14.532535 — Posted: 2023-03-14
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology
Balana, A. T., Mahul-Mellier, A.-L., Nguyen, B. A., Horvath, M., Javed, A., Hard, E. R., Jasiqi, Y., Singh, P., Afrin, S., Pedretti, R., Singh, V., Lee, V. M.-Y., Luk, K. C., Saelices, L., Lashuel, H. A., Pratt, M. R.
10.1101/2023.03.07.531573 — Posted: 2023-03-07
L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Garza, R., Atacho, D., Adami, A., Gerdes, P., Vinod, M., Hsieh, P., Karlsson, O., Horvath, V., Johansson, P. A., Pandiloski, N., Matas, J., Quaegebeur, A., Kouli, A., Sharma, Y., Jonsson, M. E., Monni, E., Englund, E., Eichler, E. E., Gale Hammell, M., Barker, R. A., Kokaia, Z., Douse, C. H., Jakobsson, J.
10.1101/2023.03.04.531072 — Posted: 2023-03-06
Tau protein aggregation associated with SARS-CoV-2 main protease
Eberle, R. J., Coronado, M. A., Gering, I., Korostov, K., Stefanski, A., Stuehler, K., Kraemer-Schulien, V., Bloemeke, L., Bannach, O., Willbold, D.
10.1101/2023.03.04.531078 — Posted: 2023-03-06
MerTK mediates the immunologically silent uptake of alpha-synuclein fibrils by human microglia
Dorion, M.-F., Senkevich, K., Yaqubi, M., Kieran, N. W., Chen, C. X.- Q., MacDonald, A., Luo, W., Wallis, A., Shlaifer, I., Hall, J., Dudley, R. W. R., Glass, I. A., Birth Defects Research Laboratory, , Straton, J. A., Fon, E. A., Bartels, T., Antel, J. P., Gan-Or, Z., Durcan, T. M., Healy, L. M.
10.1101/2023.03.04.531108 — Posted: 2023-03-05
From Policy to Practice: Tracking an Open Science Funding Initiative
Ratan, K., Dumanis, S. B., McIntosh, S., Shah, H. V., Lewis, M., Vines, T. H., Schekman, R., Riley, E. A. U.
10.1101/2023.02.27.530238 — Posted: 2023-02-28
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., Pfeffer, S. R.
10.1101/2023.02.17.529028 — Posted: 2023-02-18

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