COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

30,496 Articles (22,363 medRxiv, 8,133 bioRxiv)

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K5 polysaccharides inhibit SARS-CoV-2 infection by preventing spike-proteolytic priming
Milanesi, M., Urbinati, C., Zimmermann, L., Oreste, P., Zani, A., Caruso, A., Caccuri, F., Laketa, V., Chlanda, P., Wade, R. C., Rusnati, M., Paiardi, G.
10.1101/2025.04.23.650164 — Posted: 2025-04-24
COVID-19 in Space: Possible Health Risks and Preparedness Guidelines
Vashishat, I., Han, E., Assogba, B. D.
10.1101/2025.04.23.650113 — Posted: 2025-04-24
In Vitro and Viral Evolution Convergence Reveal the Selective Pressures Driving Omicron Emergence
Shoshany, A., Tian, R., Blanco, M. P., Hruska, A., Konar, A., Baxova, K., Zoler, E., Mokrejs, M., Schreiber, G., Zahradnik, J.
10.1101/2025.04.23.650148 — Posted: 2025-04-24
Characterization of betacoronavirus HKU-1 and OC43 internal proteins using a prototypic coronavirus
Gunawardene, C. D., Pandey, I., Chatterjee, S., Penaflor-Tellez, Y., Odle, A., Messyasz, A., Rajsbaum, R., Sariol, A., Wong, L.-Y. R.
10.1101/2025.04.23.650176 — Posted: 2025-04-24
A flaw in using pre-trained pLLMs in protein-protein interaction inference models
Szymborski, J., Emad, A.
10.1101/2025.04.21.649858 — Posted: 2025-04-23
Harnessing the Power of Single-Cell Large Language Models with Parameter Efficient Fine-Tuning using scPEFT
He, F., Fei, R., Krull, J. E., Zhang, X., Gao, M., Su, L., Chen, Y., Yu, Y., Li, J., Jin, B., Chang, Y., Ma, A., Ma, Q., Xu, D.
10.1101/2025.04.21.649754 — Posted: 2025-04-23
SARS-CoV-2 causes chronic lung inflammation and impaired respiratory capacity in aged Roborovski dwarf hamsters
Karimi, A., Lieber, C. M., Sakamoto, K., Plemper, R. K.
10.1101/2025.04.23.650177 — Posted: 2025-04-23
Interprotomer Crosstalk in Mosaic Viral Glycoprotein Trimers Provides Insight into Polyvalent Immunogen Co-assembly
Chen, C., Lovendahl, K., Overbaugh, J., Lee, K. K.
10.1101/2025.04.22.649918 — Posted: 2025-04-23
FMed-Diffusion Federated Learning on Medical Image Diffusion
Perumal, M., Srinivas, M.
10.1101/2025.04.22.649958 — Posted: 2025-04-23
CXCL13/CXCR5 Chemokine Axis Promotes CXCR5+CD19+ B-Cell and Follicular/Effector CXCR5+CD4+ T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta Variant
Vahed, H., Chentoufi, A., Prakash, S., Quadiri, A., Karan, S., Lekhbach, Y., Omorogieva, E., Patel, S. J., Tadros, J., Liao, E. J., Lau, L. S. L., Tifrea, D. F., BENMOHAMED, L.
10.1101/2025.04.18.649623 — Posted: 2025-04-22

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).