COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,526 Articles (22,380 medRxiv, 8,146 bioRxiv)

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Dissecting serum polyclonal antibody escape to SARS-CoV-2 variants by deep mutational learning
Shlesinger, D., Sadilek, V., Minot, M., Stamkopoulos, E., Bikias, T., Kuhn, R., Agrafiotis, A., Taft, J. M., Yermanos, A., Reddy, S. T.
10.1101/2025.05.01.651552 — Posted: 2025-05-02
Modeling epithelial and endothelial cell tropism for SARS-CoV-2 through restricted transgenic hACE2 expression in mice
Lameire, S., Debeuf, N., Deckers, J., De Wolf, C., Vanheerswynghels, M., Toussaint, W., De Vlieger, L., Van Hoecke, L., De Cae, S., Schepens, B., Vanhee, S., Lambrecht, B. N.
10.1101/2025.05.01.651662 — Posted: 2025-05-02
Expression and Characterization of SARS-CoV-2 Spike Protein in Thermothelomyces heterothallica C1
Ophir, Y., Wong, J., Haddad, K. R., Huuskonen, A., Karmaker, A., Gore, V., Jung, S., Oloumi, A., Liu, Y., Fu, J., Zhang, L., Huang, P., Minami, S. A., Garimella, S. S., Thyagatur, A., Zaini, P. A., Vitikainen, M., Tchelet, R., Valbuena, N., Fuerst, T., Korkmaz, E., Falo, L. D., Balmert, S. C., Mahendiratta, S., Emalfarb, M., Shah, P., Siegel, J. B., Dandekar, A. M., Chen, X., Lebrilla, C. B., Faller, R., Saloheimo, M., McDonald, K. A., Nandi, S.
10.1101/2025.05.01.651343 — Posted: 2025-05-02
Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1
Guo, C., Yu, Y., Liu, J., Jian, F., Yang, S., Song, W., Shao, F., Yu, L., Cao, Y.
10.1101/2025.04.30.651462 — Posted: 2025-05-01
RECUR: Identifying recurrent amino acid substitutions from multiple sequence alignments
Robbins, E. H., Liu, Y., Kelly, S.
10.1101/2025.04.29.651261 — Posted: 2025-04-30
Kozak sequence libraries for characterizing transgenes across expression levels
Shukla, N., Kamath, N. D., Snell, J. C., Bruchez, A. M., Matreyek, K. A.
10.1101/2025.04.28.651141 — Posted: 2025-04-30
MAVS Orchestrates a Potent IFN-independent Antiviral Immunity by Preserving Mitochondrial Integrity
Sah, V., Potharaju, P. S., Nair, K. S., Sahoo, P. P., Pooja, A. R., Basu, D., Tandel, D., Varadarajan, K. S., Chauhan, S., Patel, A. B., Harshan, K. H.
10.1101/2025.04.28.651145 — Posted: 2025-04-30
Robust and Reliable de novo Protein Design: A Flow-Matching-Based Protein Generative Model Achieves Remarkably High Success Rates
Yan, J., Cui, Z., Yan, W., Chen, Y., Pu, M., Li, S., Ye, S.
10.1101/2025.04.29.651154 — Posted: 2025-04-29
mRNA-delivered neutralizing antibodies confer protection against SARS-CoV-2 variant in the lower and upper respiratory tract
Hazell, N. C., Reyna, R. A., Bonam, S. R., Bei, J., Kumar, N., Nguyen, T. N., Plante, J. A., Walker, D. H., Wang, T., Plante, K. S., Hu, H.
10.1101/2025.04.28.650951 — Posted: 2025-04-29
Highly potent antiviral drug candidates targeting SARS-CoV-2 nsp3 and nsp5
Galais, M., HERLEM, G., HAIDAR AHMAD, S., Pasquereau, S., EL BABA, R., BELLEFROID, M., PLANT, E., MOROT-BIZOT, S., PICAUD, F., HERBEIN, G., Van Lint, C. M.
10.1101/2025.04.28.650947 — Posted: 2025-04-29

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).