Channel:  UK Biobank

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

170 Articles

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention
Inouye, M., Abraham, G., Nelson, C. P., Wood, A. M., Sweeting, M. J., Dudbridge, F., Lai, F. Y., Kaptoge, S., Brozynska, M., Wang, T., Ye, S., Webb, T. R., Rutter, M. K., Tzoulaki, I., Patel, R. S., Loos, R. J., Keavney, B., Hemingway, H., Thompson, J., Watkins, H., Deloukas, P., Di Angelantonio, E., Butterworth, A. S., Danesh, J., Samani, N. J.
10.1101/250712 — Posted: 2018-01-19
Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use
Pasman, J. A., Verweij, K. J. H., Gerring, Z., Stringer, S., Sanchez-Roige, S., Treur, J. L., Abdellaoui, A., Nivard, M. G., Baselmans, B. M. L., Ong, J.-S., Ip, H. F., van der Zee, M. D., Bartels, M., Day, F. R., Fontanillas, P., Elson, S. L., the 23andMe Research Team, , de Wit, H., Davis, L. K., MacKillop, J., International Cannabis Consortium, , Derringer, J. L., Branje, S. J. T., Hartman, C. A., Heath, A. C., van Lier, P. A. C., Madden, P. A. F., Magi, R., Meeus, W., Montgomery, G. W., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Paus, T., Ribases, M., Kaprio, J., Boks, M. P. M
10.1101/234294 — Posted: 2018-01-08
Is a large eye size a risk factor for myopia? A Mendelian randomization study
Plotnikov, D., Guggenheim, J., The UK Biobank Eye and Vision Consortium
10.1101/240283 — Posted: 2017-12-29
Searching for the causal effects of BMI in over 300 000 individuals, using Mendelian randomization
Millard, L. A. C., Davies, N. M., Tilling, K., Gaunt, T. R., Davey Smith, G.
10.1101/236182 — Posted: 2017-12-19
The complement system supports normal postnatal development and gonadal function in both sexes
Lee, A., Rusch, J., Usmani, A., Lima, A., Wong, W., Huang, N., Lepamets, M., Vigh-Conrad, K., Worthington, R., Magi, R., Niederhuber, J., Wu, X., Atkinson, J., Hess, R., Conrad, D.
10.1101/233825 — Posted: 2017-12-14
Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P., Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J. F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L. F., Graf
10.1101/144410 — Posted: 2017-12-13
Is there association between APOE e4 genotype and structural brain ageing phenotypes, and does that association increase in older age in UK Biobank? (N = 8,395)
Lyall, D. M., Cox, S. R., Lyall, L. M., Celis-Morales, C., Cullen, B., Mackay, D. F., Ward, J., Strawbridge, R. J., McIntosh, A. M., Sattar, N., Smith, D. J., Cavanagh, J., Deary, I. J., Pell, J. P.
10.1101/230524 — Posted: 2017-12-08
Mutations in RPL3L and MYZAP increase risk of atrial fibrillation
Thorolfsdottir, R. B., Sveinbjornsson, G., Sulem, P., Jonsson, S., Halldorsson, G., Melsted, P., Ivarsdottir, E. V., Davidsson, O. B., Kristjansson, R. B., Thorleifsson, G., Helgadottir, A., Gretarsdottir, S., Norddahl, G., Rajamani, S., Torfason, B., Valgardsson, A. S., Sverrisson, J. T., Tragante, V., Asselbergs, F. W., Roden, D. M., Darbar, D., Pedersen, T. R., Sabatine, M. S., Lochen, M.-L., Halldorsson, B. V., Jonsdottir, I., Arnar, D. O., Thorsteinsdottir, U., Gudbjartsson, D. F., Holm, H., Stefansson, K.
10.1101/223578 — Posted: 2017-11-21
Circulating selenium and prostate cancer risk: a Mendelian randomization analysis
Yarmolinsky, J., Bonilla, C., Haycock, P. C., Langdon, R. J., Lotta, L. A., Langenberg, C., Relton, C. L., Lewis, S. J., Evans, D. M., the PRACTICAL consortium, , Smith, G. D., Martin, R. M.
10.1101/223248 — Posted: 2017-11-21
Leveraging polygenic functional enrichment to improve GWAS power
Kichaev, G., Bhatia, G., Loh, P.-R., Gazal, S., Burch, K., Freund, M., Scoech, A., Pasaniuc, B., Price, A.
10.1101/222265 — Posted: 2017-11-20

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