Channel: Stowers Institute for Medical Research

This collection includes bioRxiv and medRxiv papers from authors at Stowers Institute for Medical Research.

256 Articles

Single-cell multi-omics, spatial transcriptomics and systematic perturbation decode circuitry of neural crest fate decisions

Hu, Z., Mayes, S., Wang, W., Santos-Pereira, J. M., Theis, F., Sauka-Spengler, T.

10.1101/2024.09.17.613303 — Posted: 2024-09-17

Epigenetic control and inheritance of rDNA arrays

Potapova, T. A., Kostos, P., McKinney, S. A., Borchers, M., Haug, J. S., Guarracino, A., Solar, S., Gogol, M. M., Monfort Anez, G., Gomes de Lima, L., Wang, Y., Hall, K. E., Hoffman, S., Garrison, E., Phillippy, A. M., Gerton, J. L.

10.1101/2024.09.13.612795 — Posted: 2024-09-16

High-quality peptide evidence for annotating non-canonical open reading frames as human proteins

Deutsch, E. W., Kok, L. W., Mudge, J. M., Ruiz-Orera, J., Fierro-Monti, I., Sun, Z., Abelin, J. G., Alba, M. M., Aspden, J. L., Bazzini, A. A., Bruford, E., Brunet, M. A., Calviello, L., Carr, S. A., Carvunis, A.-R., Chothani, S., Clauwaert, J., Dean, K., Faridi, P., Frankish, A., Hubner, N., Ingolia, N., Magrane, M., Martin, M. J., Martinez, T. F., Menschaert, G., Ohler, U., Orchard, S., Rackham, O., Roucou, X., Slavoff, S. A., Valen, E., Wacholder, A. C., Weissman, J. S., Wu, W., Xie, Z., Choudhary, J., Bassani-Sternberg, M., Vizcaino, J. A., Ternette, N., Moritz, R. L., Prensner, J., van He

10.1101/2024.09.09.612016 — Posted: 2024-09-09

Chamaeleo calyptratus (veiled chameleon) chromosome-scale genome assembly and annotation provides insights into the evolution of reptiles and developmental mechanisms.

Shylo, N., Price, A., Robb, S., Kupronis, R., Guzman Mendez, I. A., DeGraffenreid, D., Gamble, T., Trainor, P.

10.1101/2024.09.03.611012 — Posted: 2024-09-07

PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

Chahine, Z. M., Gupta, M., Lenz, T., Hollin, T., Abel, S., Banks, C., Saraf, A., Prudhomme, J., Bhanvadia, S., Florens, L., Le Roch, K. G.

10.1101/2023.09.11.557253 — Posted: 2024-08-28

Borrelia burgdorferi BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins

Murphy, B. T., Wiepen, J. J., Graham, D. E., Swanson, S., Kashipathy, M. M., Cooper, A., Battaile, K. P., Johnson, D. K., Florens, L., Blevins, J. S., Lovell, S., Zückert, W. R.

10.1101/2024.08.06.606844 — Posted: 2024-08-07

Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen Cryptococcus neoformans

Billmyre, R. B., Craig, C., Lyon, J. W., Reichardt, C., Eickbush, M. T., Zanders, S. E.

10.1101/2024.07.28.605507 — Posted: 2024-08-06

Interpreting the CTCF-mediated sequence grammar of genome folding with AkitaV2

Smaruj, P. N., Kamulegeya, F., Kelley, D. R., Fudenberg, G.

10.1101/2024.08.01.606065 — Posted: 2024-08-04

Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells

Varberg, K. M., Moreno-Irusta, A., Novoa, A., Musser, B., Varberg, J. M., Goering, J. P., Saadi, I., Okae, H., Arima, T., Williams, J., Pisarska, M. D., Soares, M. J.

10.1101/2022.12.07.22283218 — Posted: 2024-07-23

Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones

Dong, R., Li, H., He, X. C., Wang, C., Perera, A., Malloy, S., Russell, J., Li, W., Petentler, K., Mao, X., Yang, Z., Epp, M., Hall, K., Scott, A., McKinney, M. C., Huang, S., Smith, S., Hembree, M., Wang, Y., Yu, Z., Haug, J., Unruh, J., Slaughter, B., Kang, X., Li, L.

10.1101/2024.06.28.601225 — Posted: 2024-07-17

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