Channel: Case Western Reserve University

This collection includes bioRxiv and medRxiv papers from authors at Case Western Reserve University.

1113 Articles

Engineering site-selective incorporation of fluorine into natural product analogs

Sirirungruang, S., Ad, O., Privalsky, T. M., Ramesh, S., Sax, J. L., Dong, H., Baidoo, E. E., Amer, B., Khosla, C., Chang, M. C.

10.1101/2021.08.09.455754 — Posted: 2021-08-10

Repair of Noise-Induced Damage to Stereocilia F-actin Cores is Facilitated by XIRP2

Wagner, E. L., Im, J.-S., Nakahata, M. I., Imbery, T. E., Li, S., Chen, D. B., Noy, Y., Archer, D. W., Xu, W., Hashisaki, G. T., Avraham, K. B., Shin, J.-B.

10.1101/2021.08.10.455815 — Posted: 2021-08-10

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.

Zhang, C., Verma, A., Feng, Y., Melo, M. C. R., McQuillan, M., Hansen, M., Lucas, A., Park, J., Ranciaro, A., Thompson, S., Rubel, M. A., Campbell, M. C., Beggs, W., HIRBO, J., Mpoloka, S. W., Mokone, G. G., Regeneron Genetic Center, , Nyambo, T., Meskel, D. W., Belay, G., Fokunang, C., Njamnshi, A. K., Omar, S. A., Williams, S., Rader, D., Ritchie, M. D., de la Fuente Nunez, C., Sirugo, G., Tishkoff, S.

10.1101/2021.06.28.21259529 — Posted: 2021-08-09

Multispectral Imaging for MicroChip Electrophoresis Enables Point-of-Care Newborn Hemoglobin Variant Screening

An, R., Huang, Y., Rocheleau, A., Avanaki, A., Thota, P., Man, Y., Sekyonda, Z., Segbefia, C., Dei-Adomakoh, Y., Mensah, E., Odame, I., Gurkan, U.

10.1101/2021.08.05.21261678 — Posted: 2021-08-08

Distribution of rare LOXL1 missense alleles, haplotypes and diplotypes suggests association with reduced risk of glaucoma-related exfoliation syndrome.

Igo, R. P., Kinzy, T. G., Cooke Bailey, J. N., Khor, C. C., Aung, T., Ritch, R., Sit, A. J., Lee, R. K., Pericak-Vance, M., Kang, J. H., Haines, J. L., Pasquale, L. R., Wiggs, J. L.

10.1101/2021.08.05.21261676 — Posted: 2021-08-08

Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307

Shropshire, W. C., Dinh, A. Q., Earley, M., Komarow, L., Panesso, D., Rydell, K., Gomez-Villegas, S. I., Miao, H., Hill, C., Chen, L., Patel, R., Fries, B. C., Abbo, L., Cober, E., Revolinski, S., Luterbach, C. L., Chambers, H., Fowler, V. G., Bonomo, R. A., Shelburne, S. A., Kreiswirth, B. N., van Duin, D., Hanson, B. M., Arias, C. A.

10.1101/2021.08.04.21261380 — Posted: 2021-08-08

Liver Endothelium Promotes HER3-mediated Cell Survival in KRAS Wild-type and Mutant Colorectal Cancer Cells

Rathore, M., Wright, M., Bhattacharya, R., Fan, F., Vaziri-Gohar, A., Winter, J., Wang, Z., Markowitz, S., Willis, J., Ellis, L., Wang, R.

10.1101/2021.04.27.441690 — Posted: 2021-08-04

Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation

Nguyen, K., Dobrowolski, C., Shukla, M., Cho, W.-K., Karn, J.

10.1101/2021.08.02.454353 — Posted: 2021-08-03

Scalable Clustering with Supervised Linkage Methods

Anibal, J., Day, A., Bahadiroglu, E., O'Neill, L., Phan, L., Peltekian, A., Erez, A., Kaplan, M., Altan-Bonnet, G., Mehta, P.

10.1101/2021.08.01.454697 — Posted: 2021-08-02

Using attentive gated neural networks to quantify the impact of non-coding variants on transcription factor binding affinity

Patel, N., Bai, H., Bush, W.

10.1101/2021.07.30.454350 — Posted: 2021-08-02

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