Channel: Case Western Reserve University

This collection includes bioRxiv and medRxiv papers from authors at Case Western Reserve University.

1082 Articles

Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project

Lee, W.-P., Choi, S. H., Shea, M. G., Cheng, P.-L., Dombroski, B. A., Pitsillides, A. N., Heard-Costa, N. L., Wang, H., Bulekova, K., Kuzma, A. B., Leung, Y. Y., Farrell, J. J., Lin, H., Naj, A., Blue, E. E., Nusetor, F., Wang, D., Boerwinkle, E., Bush, W. S., Zhang, X., De Jager, P. L., Dupuis, J., Farrer, L. A., Fornage, M., Martin, E., Pericak-Vance, M., Seshadri, S., Wijsman, E. M., Wang, L.-S., Schellenberg, G. D., Destefano, A. L., Haines, J. L., Peloso, G. M.

10.1101/2023.09.01.23294953 — Posted: 2023-09-02

Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART

Blanch-Lombarte, O., Ouchi, D., Jimenez-Moyano, E., Carabelli, J., Marin, M. A., Penya, R., Pelletier, A., Talla, A., Sharma, A., Dalmau, J., Santos, J. R., Sekaly, R.-P. A., Clotet, B., Prado, J. G.

10.1101/2022.07.13.499924 — Posted: 2023-09-01

Large-scale annotated dataset for cochlear hair cell detection and classification

Buswinka, C. J., Rosenberg, D. B., Simikyan, R. G., Osgood, R. T., Fernandez, K., Nitta, H., Hayashi, Y., Liberman, L. W., Nguyen, E., Yildiz, E., Kim, J., Jarysta, A., Renauld, J., Wesson, E., Thapa, P., Bordiga, P., McMurtry, N., Llamas, J., Kitcher, S. R., Lopez-Porras, A. I., Cui, R., Behnammanesh, G., Bird, J. E., Ballesteros, A., Velez-Ortega, A. C., Edge, A. S., Deans, M., Gnedeva, K., Shrestha, B. R., Manor, U., Zhao, B., Ricci, A. J., Tarchini, B., Basch, M., Stepanyan, R. S., Landegger, L. D., Rutherford, M., Liberman, M. C., Walters, B. J., Kros, C., Richardson, G. P., Cunningham, L

10.1101/2023.08.30.553559 — Posted: 2023-09-01

Spatial Distribution of Missense Variants within Complement Proteins Associates with Age Related Macular Degeneration

Grunin, M., de Jong, S., Palmer, E. L., Jin, B., Rinker, D., Moth, C., Capra, J. A., Haines, J. L., Bush, W., den Hollander, A., International Age-related Macular Degeneration Genomics Consortium

10.1101/2023.08.28.23294686 — Posted: 2023-08-31

Identifying X-Chromosome Variants Associated with Age-Related Macular Degeneration

Grunin, M., Igo, R. P., Song, Y. E., Blanton, S. H., Pericak-Vance, M. A., Haines, J. L., International Age-related Macular Degeneration Genomics Consortium

10.1101/2023.08.28.23294688 — Posted: 2023-08-31

Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimers Disease in individuals of African ancestry

Ray, N. R., Kunkle, B. W., Hamilton-Nelson, K., Kurup, J. T., Rajabli, F., Cosacak, M. I., Kizil, C., Jean-Francois, M., Cuccaro, M. L., Reyes-Dumeyer, D., Cantwell, L., Kuzma, A., Vance, J. M., Gao, S., Hendrie, H. C., Baiyewu, O., Ogunniyi, A., Akinyemi, R. O., Alzheimer's Disease Genetics Consortium, , Lee, W.-P., Martin, E. R., Wang, L.-S., Beecham, G. W., Bush, W. S., Farrer, L. A., Haines, J. L., Byrd, G. S., Schellenberg, G. D., Mayeux, R. P., Pericak-Vance, M. A., Reitz, C.

10.1101/2023.08.29.23294774 — Posted: 2023-08-30

An in vitro neurogenetics platform for precision disease modeling in the mouse

CORTES, D. E., ESCUDERO, M., MITRA, A., KORGAN, A. C., EDWARDS, A., Aydin, S. C., Munger, S. C., O'CONNELL, K. M. S., Reinholdt, L. G., PERA, M. F.

10.1101/2022.01.21.477242 — Posted: 2023-08-29

Mycobacterium tuberculosis-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis Pathogenesis

Hong, H., Dill-McFarland, K. A., Simmons, J. D., Peterson, G. J., Benchek, P., Mayanja-Kizza, H., Boom, W. H., Stein, C. M., Hawn, T. R.

10.1101/2023.08.28.23294698 — Posted: 2023-08-29

Benchmarking informatics approaches for virus discovery: Caution is needed when combining in silico identification methods

Hegarty, B., Riddell, J., Bastien, G. E., Langenfeld, K., Lindback, M., Saini, J. S., Wing, A., Zhang, J., Duhaime, M.

10.1101/2023.08.07.552334 — Posted: 2023-08-29

Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy

Kim, A. E., Lou, K. W., Giobbie-Hurder, A., Chang, K., Gidwani, M., Hoebel, K., Patel, J., Cleveland, M., Singh, P., Bridge, C., Ahmed, S. R., Bearce, B., Liu, W., Fuster-Garcia, E., Lee, E., Lin, N. U., Overmoyer, B., Wen, P. Y., Nayak, L., Cohen, J., Dietrich, J., Eichler, A., Heist, R., Krop, I., Lawrence, D., Ligibel, J., Tolaney, S., Mayer, E., Winer, E., Perrino, C. M., Summers, E. J., Mahar, M., Oh, K., Shih, H., Cahill, D., Rosen, B. R., Yen, Y.-F., Kalpathy-Cramer, J., Martinez-Lage, M., Sullivan, R. J., Brastianos, P. K., Emblem, K., Gerstner, E. R.

10.1101/2023.08.25.554868 — Posted: 2023-08-28

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