Channel: California Institute of Technology

This collection includes bioRxiv and medRxiv papers from authors at California Institute of Technology.

1222 Articles

Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles

Song, Y. J., Shinn, M. K., Bangru, S., Wang, Y., Sun, Q., Hao, Q., Chaturvedi, P., Freier, S. M., Perez-Pinera, P., Nelson, E. R., Belmont, A. S., Guttman, M., Prasantth, S. G., Kalsotra, A., Pappu, R. V., Kannanganattu, P. V.

10.1101/2024.10.31.621310 — Posted: 2024-10-31

Design of Novel Dehalogenases using Protein Large Language Models

Garcia, L. N., Nauber, W., Dahlgren, C., Reyes, T., Santos, J., Chung, R., Kapur, M., Barsever, M., Thomson, M., Lourenco, A.

10.1101/2024.10.28.620469 — Posted: 2024-10-31

Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation

Nagy, A., Kovacs, L., Rangone, H., Fu, J., Ladinsky, M. S., Glover, D. M.

10.1101/2024.10.28.620588 — Posted: 2024-10-31

Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.

Kennedy, D. R., Lemiere, J., Tan, C., Simental, E., Braxton, J., Maxwell, R. A., Amine, A. A., Al-Sady, B.

10.1101/2024.10.25.620326 — Posted: 2024-10-30

Synaptic composition, activity, mRNA translation and dynamics in combined single-synapse profiling using multimodal imaging

Falkovich, R., Aryal, S., Wang, J., Sheng, M., Bathe, M.

10.1101/2024.10.28.620504 — Posted: 2024-10-28

Bystander base editing interferes with visual function restoration in Leber congenital amaurosis

Lee, S.-H., Wu, J., Im, D., Hwang, G.-H., Jeong, Y. K., Jiang, H., Lee, S. J., Jo, D. H., Goddard, W. A., Kim, J. H., Bae, S.

10.1101/2024.10.23.619839 — Posted: 2024-10-27

An integrated view of the structure and function of the human 4D nucleome

The 4D Nucleome Consortium, , Dekker, J., Oksuz, B. A., Zhang, Y., Wang, Y., Minsk, M. K., Kuang, S., Yang, L., Gibcus, J. H., Krietenstein, N., Rando, O., Xu, J., Janssens, D. H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A. S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S. A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S. V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C. J., Szczepinska

10.1101/2024.09.17.613111 — Posted: 2024-10-27

The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease

Bostick, J. W., Connerly, T. J., Thron, T., Needham, B. D., de Castro Fonseca, M., Kaddurah-Daouk, R., Knight, R., Mazmanian, S. K.

10.1101/2024.05.07.593011 — Posted: 2024-10-24

Optical control of sphingolipid biosynthesis using photoswitchable sphingosines

Kol, M., Novak, A. J. E., Morstein, J., Schroer, C., Sokoya, T., Mensing, S., Korneev, S. M., Trauner, D., Holthuis, J. C. M.

10.1101/2024.10.24.619506 — Posted: 2024-10-24

CABO-16S : A Combined Archaea, Bacteria, Organelle 16S database for amplicon analysis of prokaryotes and eukaryotes in environmental samples

Eitel, E. M., Utter, D., Connon, S., Orphan, V. J., Murali, R.

10.1101/2024.10.23.619938 — Posted: 2024-10-23

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