Channel: Oregon Health & Science University

This collection includes bioRxiv and medRxiv papers from authors at Oregon Health & Science University.

1375 Articles

Evaluation of natural killer cell tumor homing and effector function in response to CDK4/6 and AURKA inhibition in a melanoma tumor-on-a-chip platform

Chakraborty, S., Durham, C., Bharti, V., Capece, M., Davies, A., Vilgelm, A., Skardal, A.

10.1101/2025.07.09.662476 — Posted: 2025-07-11

A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification

Lee, S., Guo, Y., Kajuluri, L. P., Roh, K., Singh, K., Jiang, W., Moore, E., Tattersfield, H., Ostrom, K., Birchenough, C., Johnson, A. L., Krinsky, S., Bouchouari, H., Mahamdeh, M., Lee, L. Y., Wyant, G., Rich, S. S. S., Rotter, J. I. I., Taylor, K. D., Malik, S., Gerszten, R. E., Cruz, D. E., Tracy, R. P., Wu, H., Zhang, H., Lu, H., Kavousi, M., Shanahan, C. M., Duer, M. J., Kramann, R., Nazarian, R. M., Eagleton, M. J., Chen, Y., Miller, C. L., Nigwekar, S. U., Malhotra, R.

10.1101/2025.07.08.663801 — Posted: 2025-07-10

JAK2 signalling to HNRNPA1 represses retrotransposon activity in haematopoietic stem cells

Deuel, J. W., Mararovs, A., Goosheh, S., Winder, G., Mohammed, H., Carroll, J., Chapman, M. S., Kapadia, C. D., Campbell, P., Nangalia, J., Schneider, C., Oellerich, T., Green, A. R., Loughran, S. J.

10.1101/2025.07.07.663405 — Posted: 2025-07-09

Progressive Remodeling of Global Protein Interaction Networks in a Mouse Model of Tauopathy

Lin, W., Phanse, S., van der Spek, S., Lampl, N., Stephens, M. C., Rondon Ortiz, A., Taylor, A., Hekman, R., Jiang, L., Havugimana, P., Botas, J., Emili, A., Wolozin, B.

10.1101/2025.07.05.663296 — Posted: 2025-07-06

N-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity

Ghosal, A., Sears, J. D., Hossain, M. A., Tse, E., Howell, S., Burdick, J. E., Morales, N. L., Martinez, S. A., Law, I., Streblow, Z. J., Streblow, D. N., Counago, R. M., Moorman, N. J., Heise, M. T., Willson, T. M.

10.1101/2025.06.30.662352 — Posted: 2025-07-04

The IFN I response in tumor cells is shaped by PARP7-p300/CBP interactions through distinct loss- and gain-of-function mechanisms

Siordia, I. R., Rieth, S., Jeltema, D., Morgan, R., Tullis, J., Orth, J., Yan, N., Marx, A., Cohen, M. S.

10.1101/2025.06.30.662483 — Posted: 2025-07-04

Human induced pluripotent stem cell-derived microglia with a CX3CR1-V249I genetic variant exhibit dysfunctional phenotypes and modulate neuronal growth and function

Tutrow, K. D., Harkin, J., Varghese, L. D., Hernandez, M., Huang, K.-C., Fang, Y., Wilcox, P., Bedford, L. M., Lin, T.-Y., Zhang, C., Gomes, C., Puntambekar, S. S., Bissel, S. J., Lamb, B. T., Meyer, J. S.

10.1101/2025.07.01.662163 — Posted: 2025-07-04

Sensitizing Immune-Refractory Ovarian Tumors via p53 Mutation-Tailored Immunotherapy

Chatterjee, R., Simoni-Nieves, A., Truong, A., Lindzen, M., Ozmen, F., Cherry, C., Zwicky, P., Mukherjee, S., Selvadurai, B.-R., Salame, T. M., Gupta, N., Giri, S., Kramarski, L., Avraham, Y., Weizman, E., Ozmen, T., Noronha, A., Chakrabarti, P., Ramesh-Kumar, D., Downward, J., Dahan, R., Amit, I., Velculescu, V., Brenton, J., Mills, G., Oren, M., Yarden, Y.

10.1101/2025.06.23.661120 — Posted: 2025-06-27

Methylation dynamics in the decades preceding acute myeloid leukaemia

Fonseca, A. V., Boniface, C. T., Watson, C., Hackett, S., Gabbutt, C., Ramos-Yamasaki, A. D., Tan, A. B., Montoya, J. M., Strogantsev, R., Hanssen, L., Zhang, Y., Apostolidou, S., Gentry-Maharaj, A., Esener, S., Spellman, P., Graham, T., Menon, U., Mohammed, H., Blundell, J. R.

10.1101/2025.06.26.661643 — Posted: 2025-06-27

Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review

Moreira-Sousa, D., Martins, B., Aguiar, A., Pinheiro, M., Akkerman, O. W., Aksamit, T. R., Aliberti, S., Andrejak, C., Daley, C. L., van Ingen, J., Lange, C., Lipman, M., Loebinger, M. R., Jankovic Makek, M., Morimoto, K., Thomson, R., Wagner, D., Winthrop, K. L., Yim, J.-J., Duarte, R.

10.1101/2025.06.23.25330100 — Posted: 2025-06-23

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